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Lipinski's rule of five, also known as Pfizer's rule of five or simply the rule of five (RO5), is a rule of thumb to evaluate druglikeness or determine if a chemical compound with a certain pharmacological or biological activity has chemical properties and physical properties that would likely make it an orally active drug in humans.
One may also round half away from zero (or round half toward infinity), a tie-breaking rule that is commonly taught and used, namely: If the fractional part of x is exactly 0.5, then y = x + 0.5 if x is positive, and y = x − 0.5 if x is negative.
If the n + 1 digit is 5 not followed by other digits or followed by only zeros, then rounding requires a tie-breaking rule. For example, to round 1.25 to 2 significant figures: Round half away from zero rounds up to 1.3. This is the default rounding method implied in many disciplines [citation needed] if the required rounding method is not ...
Round-by-chop: The base-expansion of is truncated after the ()-th digit. This rounding rule is biased because it always moves the result toward zero. Round-to-nearest: () is set to the nearest floating-point number to . When there is a tie, the floating-point number whose last stored digit is even (also, the last digit, in binary form, is equal ...
The radius ratio rules are a first approximation which have some success in predicting coordination numbers, but many exceptions do exist. [3] In a set of over 5000 oxides, only 66% of coordination environments agree with Pauling's first rule. Oxides formed with alkali or alkali-earth metal cations that contain multiple cation coordinations are ...
A mnemonic is a memory aid used to improve long-term memory and make the process of consolidation easier. Many chemistry aspects, rules, names of compounds, sequences of elements, their reactivity, etc., can be easily and efficiently memorized with the help of mnemonics.
A ruler with two linear scales: the metric and imperial.It includes shorter minor graduations and longer major graduations. A graduation is a marking used to indicate points on a visual scale, which can be present on a container, a measuring device, or the axes of a line plot, usually one of many along a line or curve, each in the form of short line segments perpendicular to the line or curve.
Hume-Rothery rules, named after William Hume-Rothery, are a set of basic rules that describe the conditions under which an element could dissolve in a metal, forming a solid solution. There are two sets of rules; one refers to substitutional solid solutions, and the other refers to interstitial solid solutions.