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[10] [25] Medications for depression affect the transmission of serotonin, norepinephrine, and dopamine. [10] Older and less selective antidepressants like TCAs and MAOIs inhibit the reuptake or metabolism of norepinephrine and serotonin in the brain, which results in higher concentrations of neurotransmitters. [25]
Sibutramine is the name of an SNRI based appetite suppressant with use in the treatment of obesity. This was explored in the treatment of depression, but was shown not to be effective. Both sibutramine and venlafaxine are phenethylamine-based. At high doses, both venlafaxine and sibutramine will start producing dopaminergic effects.
This is a complete list of clinically approved prescription antidepressants throughout the world, as well as clinically approved prescription drugs used to augment antidepressants or mood stabilizers, by pharmacological and/or structural classification.
Naltrexone-bupropion (Contrave®). This medication combines two drugs: bupropion (an antidepressant that may suppress appetite) and naltrexone, which is used to treat addiction. The combination is ...
It works as a GLP-1 receptor agonist to suppress appetite, similarly to semaglutide. Also available under the brand name Victoza at a lower dose, this drug is FDA-approved to treat type 2 diabetes.
Lexapro is an antidepressant that can improve your mood and make symptoms of depression, anxiety, obsessive-compulsive disorder and other mental health issues less severe, helping you to focus on ...
A 2012 review focused on antidepressants and sleep found that mirtazapine reduced the time it took to fall asleep and improved the quality of sleep in many people with sleep disorders caused by depression, but that it could also disturb sleep in many people, especially at higher doses, causing restless leg syndrome in 8 to 28% of people and in ...
Sertraline, sold under the brand name Zoloft among others, is an antidepressant medication of the selective serotonin reuptake inhibitor (SSRI) class [10] used to treat major depressive disorder, generalized anxiety disorder, social anxiety disorder, obsessive–compulsive disorder (OCD), panic disorder, and premenstrual dysphoric disorder. [11]
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