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Typhoid fever, also known simply as typhoid, is a disease caused by Salmonella enterica serotype Typhi bacteria, also called Salmonella typhi. [2] [3] Symptoms vary from mild to severe, and usually begin six to 30 days after exposure. [4] [5] Often there is a gradual onset of a high fever over several days. [4]
Murine typhus, also known as endemic typhus or flea-borne typhus, is a form of typhus transmitted by fleas (Xenopsylla cheopis), usually on rats, in contrast to epidemic typhus which is usually transmitted by lice.
Typhoid fever is caused by the bacterium Salmonella enterica Serovar Typhi. [ 37 ] In Canada alone, the typhus epidemic of 1847 killed more than 20,000 people from 1847 to 1848, mainly Irish immigrants in fever sheds and other forms of quarantine, who had contracted the disease aboard the crowded coffin ships in fleeing the Great Irish Famine .
Rickettsia typhi is a small, aerobic, obligate intracellular, rod shaped, gram negative bacterium. [1] R. typhi is a zoonotic bacterium that is recognized as a biocontainment level 2/3 organism (dependent upon the tissue being worked with).
Although fecal–oral transmission is usually discussed as a route of transmission, it is actually a specification of the entry and exit portals of the pathogen, and can operate across several of the other routes of transmission. [1] Fecal–oral transmission is primarily considered as an indirect contact route through contaminated food or water.
Typhoid Mary in a New York Hospital. Mary Mallon, known as "Typhoid Mary", was an asymptomatic carrier of Salmonella enterica serovar typhi, the causative agent of typhoid fever. [11] She was a cook for several families and soldiers in New York City during the late 1800s, and several cases of typhoid fever were traced to her by the Health ...
The fecal–oral route is a disease transmission pathway for waterborne diseases. [ citation needed ] Poverty also increases the risk of communities to be affected by waterborne diseases. For example, the economic level of a community impacts their ability to have access to clean water. [ 7 ]
Rose spots may also occur following invasive non-typhoid salmonellosis. Rose spots are bacterial emboli to the skin and occur in approximately 1/3 of cases of typhoid fever. They are one of the classic signs of untreated disease, but can also be seen in other illnesses as well including shigellosis and nontyphoidal salmonellosis.