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An experimental design or randomized clinical trial requires careful consideration of several factors before actually doing the experiment. [32] An experimental design is the laying out of a detailed experimental plan in advance of doing the experiment.
In the statistical theory of the design of experiments, blocking is the arranging of experimental units that are similar to one another in groups (blocks) based on one or more variables. These variables are chosen carefully to minimize the affect of their variability on the observed outcomes.
In the statistical theory of design of experiments, randomization involves randomly allocating the experimental units across the treatment groups.For example, if an experiment compares a new drug against a standard drug, then the patients should be allocated to either the new drug or to the standard drug control using randomization.
In the design of experiments, optimal experimental designs (or optimum designs [2]) are a class of experimental designs that are optimal with respect to some statistical criterion. The creation of this field of statistics has been credited to Danish statistician Kirstine Smith .
This article describes completely randomized designs that have one primary factor. The experiment compares the values of a response variable based on the different levels of that primary factor. For completely randomized designs, the levels of the primary factor are randomly assigned to the experimental units .
The second type is comparative research. These designs compare two or more groups on one or more variable, such as the effect of gender on grades. The third type of non-experimental research is a longitudinal design. A longitudinal design examines variables such as performance exhibited by a group or groups over time (see Longitudinal study).
Repeated measures design is a research design that involves multiple measures of the same variable taken on the same or matched subjects either under different conditions or over two or more time periods. [1] For instance, repeated measurements are collected in a longitudinal study in which change over time is assessed.
Designed experiments with full factorial design (left), response surface with second-degree polynomial (right) In statistics, a full factorial experiment is an experiment whose design consists of two or more factors, each with discrete possible values or "levels", and whose experimental units take on all possible combinations of these levels across all such factors.