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Caramboxin (CBX) is a toxin found in star fruit (Averrhoa carambola) [1] [2] and the related bilimbi fruit (Averrhoa bilimbi). [3] Individuals with some types of kidney disease are susceptible to adverse neurological effects including intoxication, seizures and even death after eating star fruit [4] and bilimbi fruit. [3]
Azathioprine is used alone or in combination with other immunosuppressive therapy to prevent rejection following organ transplantation, and to treat an array of autoimmune diseases, including rheumatoid arthritis, pemphigus, systemic lupus erythematosus, Behçet's disease, and other forms of vasculitis, autoimmune hepatitis, atopic dermatitis, myasthenia gravis, neuromyelitis optica (Devic's ...
Nephrotoxicity is toxicity in the kidneys. It is a poisonous effect of some substances , both toxic chemicals and medications , on kidney function . [ 1 ] There are various forms, [ 2 ] and some drugs may affect kidney function in more than one way.
Carambola, also known as star fruit, is the fruit of Averrhoa carambola, a species of tree native to tropical Southeast Asia. [1] [2] [3] The edible fruit has distinctive ridges running down its sides (usually 5–6). [1] When cut in cross-section, it resembles a star, giving it the name of star fruit.
Averrhoa carambola is a species of tree in the family Oxalidaceae native to tropical Southeast Asia; [1] it has a number of common names, including carambola, star fruit and five-corner. [2] It is a small tree or shrub that grows 5 to 12 m (16 to 39 ft) tall, with rose to red-purple flowers.
Nystatin, sold under the brand name Mycostatin among others, is an antifungal medication. [1] It is used to treat Candida infections of the skin including diaper rash, thrush, esophageal candidiasis, and vaginal yeast infections. [1]
Cyclophosphamide (CP), also known as cytophosphane among other names, [3] is a medication used as chemotherapy and to suppress the immune system. [4] As chemotherapy it is used to treat lymphoma, multiple myeloma, leukemia, ovarian cancer, breast cancer, small cell lung cancer, neuroblastoma, and sarcoma. [4]
Muromonab-CD3 was approved by the U.S. Food and Drug Administration (FDA) in 1986, [5] making it the first monoclonal antibody to be approved anywhere as a drug for humans. In the European Communities , it is the first drug to be approved under the directive 87/22/EWG, a precursor of the European Medicines Agency (EMA) centralised approval ...