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The drug has amnesic, anticonvulsant, anxiolytic, hypnotic, sedative, and skeletal muscle relaxant properties. [4] Chlordiazepoxide was patented in 1958 and approved for medical use in 1960. [5] It was the first benzodiazepine to be synthesized and the discovery of chlordiazepoxide was by pure chance. [6]
There are few side effects, other than vomiting, with short-term use. [1] [2] With long-term use anemia or numbness may occur. [2] It should always be given with at least 21% oxygen. [2] It is not recommended in people with a bowel obstruction or pneumothorax. [2] Use in the early part of pregnancy is not recommended. [1]
Other drugs that have been reported to potentiate rather than inhibit the effects of serotonergic psychedelics include lithium, reserpine, pindolol, and methysergide. [6] Pindolol, a beta blocker and serotonin 5-HT 1A receptor antagonist, has been reported to potentiate the hallucinogenic effects of DMT by 2- to 3-fold in humans. [33] [34]
In Overwatch 2, Kiriko is the last hero rounding out the competitive game’s launch roster. Marking the third Japanese character in the game, this new support brings a high healing output with ...
Brotizolam [3] (marketed under brand name Lendormin) is a sedative-hypnotic [4] thienotriazolodiazepine [5] drug which is a benzodiazepine analog. [6] It possesses anxiolytic, anticonvulsant, hypnotic, sedative and skeletal muscle relaxant properties, and is considered to be similar in effect to other short-acting hypnotic benzodiazepines such as triazolam or midazolam. [7]
Possible side effects include dizziness, lightheadedness, malaise, nausea, vomiting. [medical citation needed] In rare cases, chlorzoxazone may cause severe liver dysfunction. [3] On the other hand, chlorzoxazone may reduce the liver toxicity of acetaminophen by competitive inhibition. [4] It is available as a generic medication. [5]
It is not recommended for use in children between the ages of six months and three years, unless there is a compelling need. [8] In addition to epilepsy and severe anxiety, clobazam is approved in the United Kingdom as a short-term (2–4 weeks) adjunctive agent in schizophrenia and other psychotic disorders to manage anxiety or agitation. [8] [9]
Sulpiride, sold under the brand name Dogmatil among others, is an atypical antipsychotic (although some texts have referred to it as a typical antipsychotic) [10] medication of the benzamide class which is used mainly in the treatment of psychosis associated with schizophrenia and major depressive disorder, and is sometimes used in low dosage to treat anxiety and mild depression.