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Biological functions of nitric oxide are roles that nitric oxide plays within biology. Nitric oxide (nitrogen monoxide) is a molecule and chemical compound with chemical formula of N O . In mammals including humans, nitric oxide is a signaling molecule involved in several physiological and pathological processes. [ 1 ]
Sodium is a metal where humans have discovered a great deal of its total roles in the body as well as being one of the only two alkali metals that play a major role in the bodily functions. It plays an important role in maintenance of the cell membrane potential and the electrochemical gradient in the body via the sodium-potassium pump and ...
Bioinorganic chemistry is a field that examines the role of metals in biology.Bioinorganic chemistry includes the study of both natural phenomena such as the behavior of metalloproteins as well as artificially introduced metals, including those that are non-essential, in medicine and toxicology.
The journal was established in 1988 as Biology of Metals and obtained its current name in 1992. [1] It is the official journal of the International Biometals Society . According to the Journal Citation Reports , the journal has a 2020 impact factor of 2.949.
Its impact extends beyond biology, with applications in medicine, such as the development of sildenafil (Viagra), and in industry, including semiconductor manufacturing. [10] [11] Nitric oxide should not be confused with nitrogen dioxide (NO 2), a brown gas and major air pollutant, or with nitrous oxide (N 2 O), an anesthetic gas. [6]
The journal covers the broad field of nitric oxide and other similar gaseous signaling molecules such as hydrogen sulfide and carbon monoxide. Published research includes basic and clinical topics such as cell biology, molecular biology, biochemistry, immunology, pathology, genetics, physiology, pharmacology, and disease processes.
Another factor affecting the availability of metal ions was their solubilities with H 2 S. Hydrogen sulfide was abundant in the early sea giving rise to H 2 S in the prebiotic acidic conditions and HS − in the neutral (pH = 7.0) conditions. In the series of metal sulfides, insolubility increases at neutral pH following the Irving–Williams ...
Metals have been used in treatments since ancient times. The Ebers Papyrus from 1500BC is the first written account of the use of metals for treatment and describes the use of Copper to reduce inflammation and the use of iron to treat anemia. Sodium vanadate has been used since the early 20th century to treat rheumatoid arthritis.