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gentamicin/betamethasone valerate/clotrimazole – combination drug product used to treat ear disease in dogs; glycopyrrolate – emergency drug used for cardiac support; grapiprant - non-cyclooxygenase inhibiting nonsteroidal anti-inflammatory drug (NSAID)
Gentamicin/betamethasone valerate/clotrimazole is a fixed dose combination veterinary drug, sold under the trade name Otomax. [1] It is a suspension for otic use in dogs. The active ingredients are gentamicin, betamethasone valerate and clotrimazole. This drug product is used for treatment of acute external otitis. It is also used for the ...
The minimum inhibitory concentration (MIC) and minimum bactericidal concentration are used to measure in vitro activity of antimicrobial agents. They are good indicators of antimicrobial potency, but don't give any information relating to time-dependent antimicrobial killing (the so-called post antibiotic effect).
Gentamicin is composed of a number of related gentamicin components and fractions which have varying degrees of antimicrobial potency. [38] The main components of gentamicin include members of the gentamicin C complex: gentamicin C 1 , gentamicin C 1a , and gentamicin C 2 which compose approximately 80% of gentamicin and have been found to have ...
The therapeutic index (TI; also referred to as therapeutic ratio) is a quantitative measurement of the relative safety of a drug with regard to risk of overdose.It is a comparison of the amount of a therapeutic agent that causes toxicity to the amount that causes the therapeutic effect. [1]
Produces toxic free radicals that disrupt DNA and proteins. This non-specific mechanism is responsible for its activity against a variety of bacteria, amoebae, and protozoa. Mupirocin: Bactroban: Ointment for impetigo, cream for infected cuts: Inhibits isoleucine t-RNA synthetase (IleRS) causing inhibition of protein synthesis
The Dosage Index is a mathematical figure used by breeders of Thoroughbred race horses, and sometimes by bettors handicapping horse races, to quantify a horse's ability, or inability, to negotiate the various distances at which horse races are run. It is calculated based on an analysis of the horse's pedigree.
The defined daily dose (DDD) is a statistical measure of drug consumption, defined by the World Health Organization (WHO) Collaborating Centre for Drug Statistics Methodology. It is defined in combination with the ATC Code drug classification system for grouping related drugs. The DDD enables comparison of drug usage between different drugs in ...