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Serotonin syndrome (SS) is a group of symptoms that may occur with the use of certain serotonergic medications or drugs. [1] The symptoms can range from mild to severe, and are potentially fatal. [4] [5] [2] Symptoms in mild cases include high blood pressure and a fast heart rate; usually without a fever. [2]
More severe symptoms include fever, seizures, irregular heartbeat, delirium, and coma. [76] [77] [11] If signs or symptoms arise, discontinue treatment with serotonergic agents immediately. [76] It is recommended to washout 4 to 5 half-lives of the serotonergic agent before using an MAO inhibitor. [78]
The observation of this efficacy led to the monoamine hypothesis of depression, which postulates that the deficit of certain neurotransmitters is responsible for depression, and even that certain neurotransmitters are linked to specific symptoms. Normal serotonin levels have been linked to mood and behaviour regulation, sleep, and digestion ...
Being female — binge eating disorder is more common in women than men Having type 1 or type 2 diabetes — perhaps because of the increased focus on food and weight Experiencing childhood trauma ...
Selective serotonin reuptake inhibitors (SSRIs) are a class of drugs that are typically used as antidepressants in the treatment of major depressive disorder, anxiety disorders, and other psychological conditions. SSRIs increase the extracellular level of the neurotransmitter serotonin by limiting its reabsorption (reuptake) into the ...
The lifetime prevalence of PTSD is about 10-12% in women and 5-6% in men. [43] Women are also four times more likely to develop chronic PTSD compared to men. [44] There are observed differences in the types of symptoms experienced by men and women. [43]
Long COVID symptoms, such as brain fog, could be caused by a reduction in serotonin levels, new study finds. Experts explain. Researchers Find Surprising New Reason for Long COVID—Here’s What ...
You may have heard the phrase used to describe people who function at a high level despite having anxiety symptoms. People with high-functioning anxiety are typically high-achievers ...