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Location of ABCC11 with its 30 exons on chromosome 16. The important single nucleotide polymorphism (SNP) 538G → A is located on exon 4. The ABCC11 gene is present in the human genome as two alleles, differing in one nucleotide also known as a single nucleotide polymorphism (SNP). [7]
The non-functional ABCC11 allele is predominant among East Asians (80–95%), but very low among European and African populations (0–3%). [6] Most of the world's population has the gene that codes for the wet-type earwax and average body odor; however, East Asians are more likely to inherit the allele associated with the dry-type earwax and a ...
In accordance with its transport of compounds involved in axillary odor, ABCC11 alleles are strongly associated with axillary odor. [3] Asians have little or faint axillary odor, whereas Caucasians and Africans have strong axillary odor, and this has been found to be due to genetic differences in the ABCC11 gene. [3]
For those without the mutation in the ABCC11 gene, protein in those sweat glands helps transport fatty compounds, or lipids, from the cell into the sweat. The bacteria on the skin breaks down ...
Some people may carry a gene variation that helps them avoid body odor. Some people don't have body odor, even without deodorant. Here's why — and what we can learn from them.
The majority of East Asians have the ABCC11 gene (80-95%), which greatly reduces body odor and codes for dry-type earwax. [29] It is believed that this reduction in body odor may be an adaptation to colder climates by ancient Northeast Asian ancestors, although this is not definitively proven. [30]
ABCC1 is a highly conserved gene with polymorphisms occurring at very low frequencies of less than five percent. Polymorphisms in this gene are generally found in the form of a single-nucleotide polymorphism (SNP). [10] The greatest ethnic differences in polymorphisms within the ABCC1 are found between Caucasian and Asian populations.
Ear wax is a vital substance helps protect the ear canal from damage and infection. Under normal circumstances, you can leave the ear wax alone.