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Equipment on a pharmaceutical packaging line Packaging machinery is used throughout all packaging operations, involving primary packages to distribution packs. This includes many packaging processes: fabrication, cleaning, filling, sealing, combining, labeling, overwrapping, palletizing .
Many pharmaceutical products are sensitive to heat or cold. Controlled distribution systems and sometimes cold chains are required. A mail order or online pharmacy usually ships orders by mail services or by small parcel carrier. The shipment is not temperature-controlled and it may sit in a mail box upon delivery. Conditions can include high ...
One of the most important is to accurately state the quantity (weight, volume, count) of the package contents. Consumers expect that the label accurately reflects the actual contents. Manufacturers and packagers must have effective quality assurance procedures and accurate equipment; even so, there is inherent variability in all processes .
Blister packs are created by means of a form-fill-seal process at the pharmaceutical company or designated contract packer. A form-fill-seal process means that the blister pack is created from rolls of flat sheet or film, filled with the pharmaceutical product and closed (sealed) on the same equipment. Such equipment is called a blisterline.
Fillers (or filling machines) are used for packaging, mainly for food/beverage but for other products as well. These are used to fill either a bottle or a pouch, depending on the product. There are several types of fillers used by the packaging industry. The following are the most common:
Capsule fill weight is a critical attribute in encapsulation and various real-time fill weight monitoring techniques such as near-infrared spectroscopy (NIR) and vibrational spectroscopy are used, as well as in-line weight checks, to ensure product quality. [7]
The amount of loose fill material required and the transmitted shock levels vary with the specific type of material. [2] Paper Paper can be manually or mechanically wadded up and used as a cushioning material. Heavier grades of paper provide more weight-bearing ability than old newspapers. Creped cellulose wadding is also available.
In the pharmaceutical industry, fill and finish (also referred to as fill finish, fill-finish or fill/finish) is the process of filling vials with vaccine, biological and pharmaceutical Drug Substances (DS) and finishing the process of packaging the medicine for distribution. Many vaccine manufacturers use third parties to fill and finish their ...