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Sirolimus, also known as rapamycin and sold under the brand name Rapamune among others, is a macrolide compound that is used to coat coronary stents, prevent organ transplant rejection, treat a rare lung disease called lymphangioleiomyomatosis, and treat perivascular epithelioid cell tumour (PEComa).
mTOR inhibitors are a class of drugs used to treat several human diseases, including cancer, autoimmune diseases, and neurodegeneration. They function by inhibiting the mammalian target of rapamycin (mTOR) (also known as the mechanistic target of rapamycin), which is a serine/threonine-specific protein kinase that belongs to the family of phosphatidylinositol-3 kinase (PI3K) related kinases ...
Sirolimus (rapamycin, trade name Rapamune) is a macrolide lactone, produced by the actinomycete bacterium Streptomyces hygroscopicus. It is used to prevent rejection reactions. Although it is a structural analogue of tacrolimus, it acts somewhat differently and has different side-effects.
The FDA (U.S. Food and Drug Administration) suggests taking Cialis at a maximum as-needed dosage of 10 milligrams no more than once per 72 hours — or a daily dosage of 2.5 milligrams — if you ...
Everolimus, sold under the brand name Afinitor among others, is a medication used as an immunosuppressant to prevent rejection of organ transplants [10] and as a targeted therapy in the treatment of renal cell cancer and other tumours. [11] This compound also has a use in cardiovascular drug-eluting stent technologies to inhibit restenosis.
Temsirolimus is a specific inhibitor of mTOR and interferes with the synthesis of proteins that regulate proliferation, growth, and survival of tumor cells. Though temsirolimus shows activity on its own, it is also known to be converted to sirolimus (rapamycin) in vivo; [4] therefore, its activity may be more attributed to its metabolite rather than the prodrug itself (despite claims to the ...
twice daily bib. bibe: drink bis bis: twice b.i.d., b.d. bis in die: twice daily AMA style avoids use of this abbreviation (spell out "twice a day") bis ind. bis indies: twice a day bis in 7 d. bis in septem diebus: twice a week BM bowel movement: commonly used in the United Kingdom when discussing blood sugar.
Common side effects of the drug include "nausea, vomiting, diarrhea, infections, decreased appetite, and fatigue". [13] Other treatment options have focused on reducing complications (such as cardiovascular disease) with coronary artery bypass surgery and low-dose acetylsalicylic acid. [51] Growth hormone treatment has been attempted. [52]
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related to: rapamune side effects sirolimus medication dosage for women over 50 daily- 109 S High St #100, Columbus, OH · Directions · (614) 224-4261
"The lowest prices on specific drugs" - Family Circle