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The ileocecal valve [a] is a sphincter muscle valve that separates the small intestine and the large intestine. [1] Its critical function is to limit the reflux of colonic contents into the ileum. [2] Approximately two liters of fluid enters the colon daily through the ileocecal valve.
In the lower part of the descending portion, below the point where the bile and pancreatic ducts enter the small intestine, they are very large and closely approximated. In the horizontal and ascending portions of the duodenum and upper half of the jejunum , they are large and numerous. [ 3 ]
The cecum is a pouch marking the division between the small intestine and the large intestine. It lies below the ileocecal valve in the lower right quadrant of the abdomen. [33] The cecum receives chyme from the last part of the small intestine, the ileum, and connects to the ascending colon of the large intestine. At this junction there is a ...
It follows the jejunum and ends at the ileocecal junction, where the terminal ileum communicates with the cecum of the large intestine through the ileocecal valve. The ileum, along with the jejunum, is suspended inside the mesentery , a peritoneal formation that carries the blood vessels supplying them (the superior mesenteric artery and vein ...
The epithelium, the most exposed part of the mucosa, is a glandular epithelium with many goblet cells. Goblet cells secrete mucus, which lubricates the passage of food along and protects the intestinal wall from digestive enzymes. In the small intestine, villi are folds of the
The junction between the small intestine and the colon, called the ileocecal valve, is so small in some animals that it was not considered to be a connection between the small and large intestines. During a dissection, the colon could be traced from the rectum , to the sigmoid colon , through the descending , transverse , and ascending sections.
The large intestine is truly distinct only in tetrapods, in which it is almost always separated from the small intestine by an ileocaecal valve. In most vertebrates, however, it is a relatively short structure running directly to the anus, although noticeably wider than the small intestine.
A valve system in place here prevents the absorbed lymph from leaking back into the interstital fluid. This valve system involves collagen fibers attached to lymphatic endothelial cells that respond to increased interstitial fluid pressure by separating the endothelial cells and allowing the flow of lymph into the capillary for circulation. [5]