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  2. Treatment and management of COVID-19 - Wikipedia

    en.wikipedia.org/wiki/Treatment_and_management...

    The principal for obstetric management of COVID-19 include rapid detection, isolation, and testing, profound preventive measures, regular monitoring of fetus as well as of uterine contractions, peculiar case-to-case delivery planning based on severity of symptoms, and appropriate post-natal measures for preventing infection.

  3. Nirmatrelvir/ritonavir - Wikipedia

    en.wikipedia.org/wiki/Nirmatrelvir/ritonavir

    No participants had received a COVID‑19 vaccine or been previously infected with COVID‑19. [12] The main outcome measured in the trial was the proportion of people who were hospitalized due to COVID‑19 or died due to any cause during 28 days of follow-up. [12] EPIC-HR started in July 2021, and completed in December 2021. [49]

  4. First pass effect - Wikipedia

    en.wikipedia.org/wiki/First_pass_effect

    [1] [2] The effect is most associated with orally administered medications, but some drugs still undergo first-pass metabolism even when delivered via an alternate route (e.g., IV, IM, etc.). [3] During this metabolism, drug is lost during the process of absorption which is generally related to the liver and gut wall. The liver is the major ...

  5. Coronavirus symptoms start slow, and worsen quickly ... - AOL

    www.aol.com/article/news/2020/03/24/coronavirus...

    As the new coronavirus spreads, doctors are seeing a pattern emerge in the way people are responding to the disease. People at first will experience mild symptoms like a light cough or headache.

  6. Journal pulls scientific paper that popularized ... - AOL

    www.aol.com/journal-pulls-scientific-paper...

    One of the most notable scientific papers that first popularized hydroxychloroquine as a COVID-19 treatment was retracted from its journal due to ethical and methodological issues. Retractions in ...

  7. Nirmatrelvir - Wikipedia

    en.wikipedia.org/wiki/Nirmatrelvir

    [9] [10] These drugs had been further developed prior to the COVID-19 pandemic for other diseases including SARS. [11] The utility of targeting the 3CL protease in a real world setting was first demonstrated in 2018 when GC376 (a prodrug of GC373) was used to treat the previously 100% lethal cat coronavirus disease, feline infectious ...

  8. COVID-19 drug development - Wikipedia

    en.wikipedia.org/wiki/COVID-19_drug_development

    Bebtelovimab is a neutralizing human immunoglobulin G1 (IgG1) monoclonal antibody, isolated from a patient who has recovered from the Coronavirus disease 2019 (COVID-19), directed against the spike (S) protein of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), that can potentially be used for immunization against COVID-19.

  9. Ritonavir - Wikipedia

    en.wikipedia.org/wiki/Ritonavir

    Ritonavir is indicated in combination with other antiretroviral agents for the treatment of HIV-1-infected patients. [4] [5] [8] Though initially developed as an independent antiviral treatment, it is most commonly used as a pharmacokinetic enhancer, in order to increase the plasma concentrations of other antiretrovirals.