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[6] [7] [8] High-risk people are more susceptible to hospitalization and death from the Coronavirus disease 2019. [9] The Centers for Disease Control and Prevention (CDC) recommends high-risk persons get the COVID-19 vaccine. [10] [9] In psychiatry, a high-risk individual is a patient who engages in high-risk behaviors. [11]
Transmission and life-cycle of SARS-CoV-2 causing COVID-19. Coronaviruses vary significantly in risk factor. Some can kill more than 30% of those infected, such as MERS-CoV, and some are relatively harmless, such as the common cold. [49] Coronaviruses can cause colds with major symptoms, such as fever, and a sore throat from swollen adenoids. [91]
SARS-CoV-2 is the seventh known coronavirus to infect people, after 229E, NL63, OC43, HKU1, MERS-CoV, and the original SARS-CoV. [105] Like the SARS-related coronavirus implicated in the 2003 SARS outbreak, SARS‑CoV‑2 is a member of the subgenus Sarbecovirus (beta-CoV lineage B). [106] [107] Coronaviruses undergo frequent recombination. [108]
The COVID-19 vaccines are widely credited for their role in reducing the severity and death caused by COVID-19. [ 128 ] [ 129 ] As of March 2023, more than 5.5 billion people had received one or more doses [ 130 ] (11.8 billion in total) in over 197 countries.
Scanning electron micrograph of SARS virions. Severe acute respiratory syndrome (SARS) is the disease caused by SARS-CoV-1. It causes an often severe illness and is marked initially by systemic symptoms of muscle pain, headache, and fever, followed in 2–14 days by the onset of respiratory symptoms, [13] mainly cough, dyspnea, and pneumonia.
The Great Barrington Declaration is an open letter published in October 2020 in response to the COVID-19 pandemic and lockdowns. [1] [2] It claimed harmful COVID-19 lockdowns could be avoided via the fringe notion of "focused protection", by which those most at risk of dying from an infection could purportedly be kept safe while society otherwise took no steps to prevent infection.
The figures presented are based on reported cases and deaths. While in several high-income countries the ratio of total estimated cases and deaths to reported cases and deaths is low and close to 1, for some countries it may be more than 10 [7] or even more than 100. [8] Implementation of COVID-19 surveillance methods varies widely. [9]
Screenshot of a template on the English Wikipedia displaying a collection of articles related to the COVID-19 pandemic, as of 3 April 2021. A year after its first creation, the main COVID-19 pandemic Wikipedia article in English had become the 34th most viewed article on the website of all time, with almost 32,000 inbound links from other articles, according to The New Republic. [2]
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