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Clostridioides difficile infection [5] (CDI or C-diff), also known as Clostridium difficile infection, is a symptomatic infection due to the spore-forming bacterium Clostridioides difficile. [6] Symptoms include watery diarrhea, fever, nausea, and abdominal pain. [1] It makes up about 20% of cases of antibiotic-associated diarrhea. [1]
Transmission-based precautions are infection-control precautions in health care, in addition to the so-called "standard precautions". They are the latest routine infection prevention and control practices applied for patients who are known or suspected to be infected or colonized with infectious agents, including certain epidemiologically important pathogens, which require additional control ...
Clostridioides difficile (syn. Clostridium difficile) is a bacterium known for causing serious diarrheal infections, and may also cause colon cancer. [ 4 ] [ 5 ] It is known also as C. difficile , or C. diff ( / s iː d ɪ f / ), and is a Gram-positive species of spore -forming bacteria. [ 6 ]
Clostridioides difficile, also known more commonly as C. diff, accounts for 10 to 20% of antibiotic-associated diarrhea cases, because the antibiotics administered for the treatment of certain disease processes such as inflammatory colitis also inadvertently kill a large portion of the gut flora, the normal flora that is usually present within the bowel.
Hydrogen peroxide is effective against endospore-forming bacteria, such as Clostridioides difficile, whereas alcohol is ineffective. [29] [non-primary source needed] Ultraviolet cleaning devices may also be used to disinfect the rooms of patients infected with Clostridioides difficile or methicillin-resistant Staphylococcus aureus after discharge.
No laboratory standards have been agreed upon, [41] so recommendations vary for size of sample to be prepared, ranging from 30 to 100 grams (1.1 to 3.5 ounces) of fecal material for effective treatment. [13] [37] [39] [42] Fresh stool is used to increase viability of bacteria within the stool [41] [42] and samples are prepared within 6–8 hours.
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