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Up to 50% by volume and 70% by weight of human bone is a modified form of hydroxyapatite, known as bone mineral. [7] Carbonated calcium-deficient hydroxyapatite is the main mineral of which dental enamel and dentin are composed. Hydroxyapatite crystals are also found in pathological calcifications such as those found in breast tumors, [8] as ...
Microcrystalline hydroxyapatite and ossein-hydroxyapatite are forms of calcium phosphate used as a dietary supplement. [36] Bone meal as a calcium supplementation has largely been discontinued due to concerns of contamination with heavy metals such as lead, arsenic, mercury, and cadmium identified in the 1980s.
The two major components of bone are hydroxyapatite [Ca10(PO4)6(OH)2], and collagen fibers. Hydroxyapatite, which is one of the most stable forms of calcium phosphate, makes up about 60 to 65 percent of the bone. [5] The rest of the bone is composed of materials including chondroitin sulfate, keratan sulfate and lipid. [5]
[7] [8] The bisphosphonates have an intrinsic affinity for the calcium ions (hydroxyapatite) of the bone mineral just as the endogenous pyrophosphates. The difference lies in the non-hydrolysable carbon-phosphorus bond of the bisphosphonates which prevents their metabolism and at the same time ensure an effective absorption from the ...
Bone meal (or bonemeal) is a mixture of finely and coarsely ground animal bones and slaughter-house waste products. [1] It is used as a dietary supplement to supply calcium and phosphorus to monogastric livestock in the form of hydroxyapatite. As a slow-release organic fertilizer, it supplies phosphorus, calcium, and a small amount of nitrogen ...
The mineral in bone (known as bone mineral) is hydroxyapatite with a lot of carbonate ions, while the organic portion is made mostly of collagen and some other proteins. The hierarchical structural of bone spans across to a three tiered hierarchy of the collagen molecule itself. [ 14 ]
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