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  2. IFNB1 - Wikipedia

    en.wikipedia.org/wiki/IFNB1

    Interferon beta is a protein that in humans is encoded by the IFNB1 gene. [5] The natural and recombinant protein forms have antiviral, antibacterial, and anticancer properties. Interferon beta 1a (tradenames: Avonex and Rebif) and Interferon beta 1b (tradenames: Betaseron/Betaferon) are used as drugs.

  3. Interferon - Wikipedia

    en.wikipedia.org/wiki/Interferon

    For example, in January 2001, the Food and Drug Administration (FDA) approved the use of PEGylated interferon-alpha in the USA; in this formulation, PEGylated interferon-alpha-2b (Pegintron), polyethylene glycol is linked to the interferon molecule to make the interferon last longer in the body.

  4. Interferon type I - Wikipedia

    en.wikipedia.org/wiki/Interferon_type_I

    The type-I interferons (IFN) are cytokines which play essential roles in inflammation, immunoregulation, tumor cells recognition, and T-cell responses. In the human genome, a cluster of thirteen functional IFN genes is located at the 9p21.3 cytoband over approximately 400 kb including coding genes for IFNα (IFNA1, IFNA2, IFNA4, IFNA5, IFNA6, IFNA7, IFNA8, IFNA10, IFNA13, IFNA14, IFNA16 ...

  5. IFNW1 - Wikipedia

    en.wikipedia.org/wiki/IFNW1

    3467 n/a Ensembl ENSG00000177047 n/a UniProt P05000 n/a RefSeq (mRNA) NM_002177 n/a RefSeq (protein) NP_002168 n/a Location (UCSC) Chr 9: 21.14 – 21.14 Mb n/a PubMed search n/a Wikidata View/Edit Human Interferon omega-1 is a protein that is encoded by the IFNW1 gene. Introduction Interferon omega-1 (IFN-ω) is a subtype of the Interferon type I family. The Interferon Type 1 family is made ...

  6. IFIT1 - Wikipedia

    en.wikipedia.org/wiki/IFIT1

    112419 Ensembl n/a ENSMUSG00000067297 UniProt P09914 Q3U687 RefSeq (mRNA) NM_001548 NM_001270927 NM_001270928 NM_001270929 NM_001270930 NM_053217 NM_001362130 RefSeq (protein) NP_001257856 NP_001257857 NP_001257858 NP_001257859 NP_001539 NP_444447 NP_001349059 Location (UCSC) n/a Chr 19: 34.59 – 34.62 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Interferon-induced protein with ...

  7. Interferon beta-1a - Wikipedia

    en.wikipedia.org/wiki/Interferon_beta-1a

    Interferon beta-1a (also interferon beta 1-alpha) is a cytokine in the interferon family used to treat multiple sclerosis (MS). [5] It is produced by mammalian cells, while interferon beta-1b is produced in modified E. coli. [6] Some research indicates that interferon injections may result in an 18–38% reduction in the rate of MS relapses. [7]

  8. Interferon regulatory factors - Wikipedia

    en.wikipedia.org/wiki/Interferon_regulatory_factors

    Interferon regulatory factors (IRF) are proteins which regulate transcription of interferons (see regulation of gene expression). [1] Interferon regulatory factors contain a conserved N-terminal region of about 120 amino acids, which folds into a structure that binds specifically to the IRF-element (IRF-E) motifs, which is located upstream of the interferon genes. [2]

  9. Interferon type III - Wikipedia

    en.wikipedia.org/wiki/Interferon_type_III

    Type III interferon receptors are expressed more specifically on epithelial cells and some immune cells such as neutrophils, and depending on the species, B cells and dendritic cells as well. [ 13 ] [ 14 ] [ 15 ] Therefore, their antiviral effects are most prominent in barriers, in gastrointestinal, respiratory and reproductive tracts.

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