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A myoma is a type of tumor that involves muscle cells. [1] There are two main types of myoma: Leiomyomas which occur in smooth muscle. [1] They most commonly occur as uterine fibroids, but may also form in other locations. Rhabdomyomas which occur in striated muscle. [1] [2] [3] They are rare tumors, occur in childhood and often become malignant.
Intramural fibroids are located within the muscular wall of the uterus and are the most common type. [22] Unless they are large, they may be asymptomatic. Intramural fibroids begin as small nodules in the muscular wall of the uterus. With time, intramural fibroids may expand inwards, causing distortion and elongation of the uterine cavity.
Leiomyoma enucleated from a uterus. External surface on left; cut surface on right. Micrograph of a small, well-circumscribed colonic leiomyoma arising from the muscularis mucosae and showing fascicles of spindle cells with eosinophilic cytoplasm and elongated, cigar-shaped nuclei Immunohistochemistry for β-catenin in uterine leiomyoma, which is negative as there is only staining of cytoplasm ...
The subserosa or tela subserosa, is a thin layer of tissue in the walls of various organs.It is a layer of connective tissue (usually of the areolar type) between the muscular layer (muscularis externa) and the serosa (serous membrane).
As with hysteroscopic myomectomy, laparoscopic myomectomy is not generally used on very large fibroids. A study of laparoscopic myomectomies conducted between January 1990 and October 1998 examined 106 cases of laparoscopic myomectomy, in which the fibroids were intramural or subserous and ranged in size from 3 to 10 cm. [3]
A hematoxylin and eosin-stained sample of the papule or nodule can be examined under a microscope to diagnose cutaneous leiomyomas. [18]All cutaneous leiomyomas typically exhibit interlacing fascicles of spindle cells with considerable levels of eosinophilic cytoplasm and a blunt-ended, elongated, cigar-shaped nucleus with perinuclear halos on cross section when stained with hematoxylin and ...
Abnormal uterine bleeding in the reproductive years comprises a complex set of disorders that include abnormalities in endocrine, endometrial and hemostatic function and a number of structural anomalies that include polyps, adenomyosis and leiomyomas or fibroids.
Angioleiomyomas present as solitary, small, slow-growing, firm, movable, subcutaneous nodules that typically measure less than 2 cm in size. Pain is the most obvious symptom of angioleiomyomas. Wind and cold exposure can set off paroxysmal episodes of pain.