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  2. Direct factor Xa inhibitors - Wikipedia

    en.wikipedia.org/wiki/Direct_factor_Xa_inhibitors

    The risk of bleeding is increased if used at the same time as other blood thinning drugs such as nonsteroidal anti-inflammatory drugs, antiplatelet drugs and heparin. [2] The blood thinning effects can be reduced if used at the same time as rifampicin and phenytoin , and increased with fluconazole .

  3. List of SJS-inducing substances - Wikipedia

    en.wikipedia.org/wiki/List_of_SJS-inducing...

    This is a list of drugs and substances that are known or suspected to cause Stevens–Johnson syndrome This is a dynamic list and may never be able to satisfy particular standards for completeness. You can help by adding missing items with reliable sources .

  4. Discovery and development of direct Xa inhibitors - Wikipedia

    en.wikipedia.org/wiki/Discovery_and_development...

    Four drugs from the class of direct Xa inhibitors are marketed worldwide. Rivaroxaban (Xarelto) was the first approved FXa inhibitor to become commercially available in Europe and Canada in 2008. [1] The second one was apixaban (Eliquis), approved in Europe in 2011 [2] and in the United States in 2012. [3]

  5. How genomic testing can personalize treatment for 150K ... - AOL

    www.aol.com/genomic-testing-personalize...

    The U.S. Food and Drug Administration has identified 27 genetic variants associated with interactions involving more than 100 drugs. The RightMed test analyzes more than 100 alleles, which are the ...

  6. Apixaban - Wikipedia

    en.wikipedia.org/wiki/Apixaban

    Compared to warfarin it has fewer interactions with other medications. [10] It is a direct factor Xa inhibitor. [6] In 2007, Pfizer and Bristol-Myers Squibb began the development of apixaban as an anticoagulant. [11] Apixaban was approved for medical use in the European Union in May 2011, and in the United States in December 2012.

  7. Grapefruit–drug interactions - Wikipedia

    en.wikipedia.org/wiki/Grapefruit–drug_interactions

    [19] [31] For drugs recently sold on the market, drugs have information pages (monographs) that provide information on any potential interaction between a medication and grapefruit juice. [19] Because there is a growing number of medications that are known to interact with citrus, [ 1 ] patients should consult a pharmacist or physician before ...

  8. Pfizer (PFE) Q3 2024 Earnings Call Transcript - AOL

    www.aol.com/pfizer-pfe-q3-2024-earnings...

    Consider when Nvidia made this list on April 15, ... We have addressed the drug-drug interactions and the metallic taste associated with PAXLOVID. ... ELIQUIS, XTANDI and NURTEC, partially offset ...

  9. Drug interaction - Wikipedia

    en.wikipedia.org/wiki/Drug_interaction

    When two drugs affect each other, it is a drugdrug interaction (DDI). The risk of a DDI increases with the number of drugs used. [1] A large share of elderly people regularly use five or more medications or supplements, with a significant risk of side-effects from drugdrug interactions. [2] Drug interactions can be of three kinds ...

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