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The process of osmosis over a semipermeable membrane.The blue dots represent particles driving the osmotic gradient. Osmosis (/ ɒ z ˈ m oʊ s ɪ s /, US also / ɒ s-/) [1] is the spontaneous net movement or diffusion of solvent molecules through a selectively-permeable membrane from a region of high water potential (region of lower solute concentration) to a region of low water potential ...
Osmoregulation is the active regulation of the osmotic pressure of an organism's body fluids, detected by osmoreceptors, to maintain the homeostasis of the organism's water content; that is, it maintains the fluid balance and the concentration of electrolytes (salts in solution which in this case is represented by body fluid) to keep the body fluids from becoming too diluted or concentrated.
Claude Bernard, French physician who introduced the concept of homeostasis. The human body and even its individual body fluids may be conceptually divided into various fluid compartments, which, although not literally anatomic compartments, do represent a real division in terms of how portions of the body's water, solutes, and suspended elements are segregated.
Semipermeable membrane is a type of synthetic or biologic, polymeric membrane that allows certain molecules or ions to pass through it by osmosis. The rate of passage depends on the pressure, concentration, and temperature of the molecules or solutes on either side, as well as the permeability of the membrane to each solute.
Transcellular transport often involves energy expenditure whereas paracellular transport is unmediated and passive down a concentration gradient, [4] or by osmosis (for water) and solvent drag for solutes. [5] Paracellular transport also has the benefit that absorption rate is matched to load because it has no transporters that can be saturated.
Current research also suggests that osmotic stress in cells and tissues may significantly contribute to many human diseases. [6] In eukaryotes, calcium acts as one of the primary regulators of osmotic stress. Intracellular calcium levels rise during hypo-osmotic and hyper-osmotic stresses.
Effect of different solutions on red blood cells Micrographs of osmotic pressure on red blood cells. In chemical biology, tonicity is a measure of the effective osmotic pressure gradient; the water potential of two solutions separated by a partially-permeable cell membrane.
Dialysis tubing is also frequently used as a teaching aid to demonstrate the principles of diffusion, osmosis, Brownian motion and the movement of molecules across a restrictive membrane. For the principles and usage of dialysis in a research setting, see Dialysis (biochemistry) .