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Chelating agents convert these metal ions into a chemically and biochemically inert form that can be excreted. Chelation using sodium calcium edetate has been approved by the U.S. Food and Drug Administration (FDA) for serious cases of lead poisoning. It is not approved for treating "heavy metal toxicity". [18]
Chelating resins are a class of ion-exchange resins. They are almost always used to bind cations, and utilize chelating agents covalently attached to a polymer matrix. Chelating resins have the same bead form and polymer matrix as usual ion exchangers. Their main use is for pre-concentration of metal ions in a dilute solution.
Chelex 100 is a chelating material from Bio-Rad [1] used to purify other compounds via ion exchange.It is noteworthy for its ability to bind transition metal ions.. It is a styrene-divinylbenzene co-polymer containing iminodiacetic acid groups.
Chelation therapy is a medical procedure that involves the administration of chelating agents to remove heavy metals from the body. [1] Chelation therapy has a long history of use in clinical toxicology [2] and remains in use for some very specific medical treatments, although it is administered under very careful medical supervision due to various inherent risks, including the mobilization of ...
Pages in category "Chelating agents" The following 164 pages are in this category, out of 164 total. ... Transition metal complexes of 2,2'-bipyridine; 2,2'-Bipyrimidine;
The His-tag binds the metal of metal chelator complexes. Previously, iminodiacetic acid was used for that purpose. Now, nitrilotriacetic acid is more commonly used. [12] For laboratory uses, Ernst Hochuli et al. (1987) coupled the NTA ligand and nickel ions to agarose beads. [13]
Like other complexing agents in the aminopolycarboxylic acid class, trisodium N-(1-carboxylatoethyl)iminodiacetate (α-ADA) finds due to its ability to form stable chelate complexes with polyvalent ions (in particular the water hardening agents Ca 2+ and Mg 2+, as well as transition and heavy metal ions such as Fe 3+, Mn 2+, Cu 2+, etc.) use in ...
Tetrasodium iminodisuccinate is a chelating agent, forming complexes of moderate stability (10 −16), which includes (as a pentadentate ligand) alkaline earth and polyvalent heavy metal ions with one molecule of water in an octahedral structure. [7] In 0.25% aqueous solution, a pH of 11.5 results for tetrasodium iminodisuccinate. The salt is ...
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