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By definition it means, to recapitulate mammalian oogenesis and producing fertilizable oocytes in vitro.it is a complex process involving several different cell types, precise follicular cell-oocyte reciprocal interactions, a variety of nutrients and combinations of cytokines, and precise growth factors and hormones depending on the ...
An ovarian follicle is a roughly spheroid cellular aggregation set found in the ovaries. It secretes hormones that influence stages of the menstrual cycle . In humans, women have approximately 200,000 to 300,000 follicles at the time of puberty , [ 1 ] [ 2 ] each with the potential to release an egg cell (ovum) at ovulation for fertilization ...
An oocyte (/ ˈ oʊ ə s aɪ t /, oöcyte, or ovocyte is a female gametocyte or germ cell involved in reproduction.In other words, it is an immature ovum, or egg cell.An oocyte is produced in a female fetus in the ovary during female gametogenesis.
During oogenesis, the oogonia become primary oocytes. Oocytes (immature ova) residing in the primordial follicle of the ovary are in a non-growing prophase arrested state, but have the capacity to undergo highly efficient homologous recombinational repair of DNA damages including double-strand breaks. [ 1 ]
In biology, folliculogenesis is the maturation of the ovarian follicle, a densely packed shell of somatic cells that contains an immature oocyte. Folliculogenesis describes the progression of a number of small primordial follicles into large preovulatory follicles that occurs in part during the menstrual cycle .
Ovulation is an important part of the menstrual cycle in female vertebrates where the egg cells are released from the ovaries as part of the ovarian cycle. In female humans ovulation typically occurs near the midpoint in the menstrual cycle and after the follicular phase. Ovulation is stimulated by an increase in luteinizing hormone (LH).
The process of ovulation and gamete production, oogenesis, in a human ovary. The ovaries are the site of production and periodical release of egg cells, the female gametes. In the ovaries, the developing egg cells (or oocytes) mature in the fluid-filled follicles. Typically, only one oocyte develops at a time, but others can also mature ...
Oogenesis is the formation of a cell who will produce one ovum and three polar bodies. [10] Oogenesis begins in the female embryo with the production of oogonia from primordial germ cells. Like spermatogenesis, the primordial germ cell undergo mitotic division to form the cells that will later undergo meiosis, but will be halted at the prophase ...