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Dry eye syndrome, also known as keratoconjunctivitis sicca, is the condition of having dry eyes. [2] Symptoms include dryness in the eye, irritation, redness, discharge, blurred vision, and easily fatigued eyes.
In contrast to the normal moisture of the eyes or even crying, there can be persistent dryness, scratching, itchiness and burning in the eyes, which are signs of dry eye syndrome (DES) or keratoconjunctivitis sicca (KCS). With this syndrome, the lacrimal glands produce less lacrimal fluid, which mainly occurs with aging or certain medications.
The lacrimal caruncle is found at the medial canthus of the eye. [1] It consists of skin, hair follicles, sebaceous glands, sweat glands, accessory lacrimal tissue and other tissues that are present in the skin and accessory lacrimal glands. [1] [2] Its non-keratinized epithelium resembles the conjunctival epithelium. [2]
Measurements of tear osmolarity may be beneficial in diagnosing concurrent dry eye syndrome (DES), which may be responsible for overlapping symptoms and would allow the physician to decipher between conditions and move forward with the most beneficial protocol for the patient.
[12] [13] Besides leading to dry eyes, the obstructions can be degraded by bacterial lipases, resulting in the formation of free fatty acids, which irritate the eyes and sometimes cause punctate keratopathy. Meibomian gland dysfunction is more often seen in women and is regarded as the main cause of dry eye disease.
Keratoconus is normally bilateral [78] (affecting both eyes) although the distortion is usually asymmetric and is rarely completely identical in both corneas. [14] Unilateral cases tend to be uncommon, and may in fact be very rare if a very mild condition in the better eye is simply below the limit of clinical detection. [ 45 ]
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