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The Immortal Life of Henrietta Lacks is a drama television film directed by George C. Wolfe and starring Oprah Winfrey and Rose Byrne.It is based on the book of the same name by Rebecca Skloot and documents the story of Henrietta Lacks, who was diagnosed with cervical cancer in the 1950s, and whose cancer cells (later known as HeLa) would change the course of cancer treatment.
HeLa cells are rapidly dividing cancer cells, and the number of chromosomes varies during cancer formation and cell culture. The current estimate (excluding very tiny fragments) is a "hypertriploid chromosome number (3n+)", which means 76 to 80 total chromosomes (rather than the normal diploid number of 46) with 22–25 clonally abnormal ...
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The book is about Henrietta Lacks and the immortal cell line, known as HeLa, that came from Lacks's cervical cancer cells in 1951. Skloot became interested in Lacks after a biology teacher referenced her but knew little about her. Skloot began conducting extensive research on her and worked with Lacks' family to create the book.
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An immortalised cell line is a population of cells from a multicellular organism that would normally not proliferate indefinitely but, due to mutation, have evaded normal cellular senescence and instead can keep undergoing division. The cells can therefore be grown for prolonged periods in vitro. The mutations required for immortality can occur ...
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