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  2. Gout - Wikipedia

    en.wikipedia.org/wiki/Gout

    Gout presenting as slight redness in the metatarsophalangeal joint of the big toe. Gout can present in several ways, although the most common is a recurrent attack of acute inflammatory arthritis (a red, tender, hot, swollen joint). [4] The metatarsophalangeal joint at the base of the big toe is affected most often, accounting for half of cases ...

  3. Your Gout Guide: From Symptoms to Treatment - AOL

    www.aol.com/lifestyle/gout-guide-symptoms...

    What Is Gout? Gout is an inflammatory form of arthritis that can occur when there’s too much uric acid in the body. Uric acid is a normal waste product made by the body, but in some people, it ...

  4. Uric acid - Wikipedia

    en.wikipedia.org/wiki/Uric_acid

    A 2011 survey in the United States indicated that 3.9% of the population had gout, whereas 21.4% had hyperuricemia without having symptoms. [ 43 ] Excess blood uric acid (serum urate) can induce gout , [ 44 ] a painful condition resulting from needle-like crystals of uric acid termed monosodium urate crystals [ 45 ] precipitating in joints ...

  5. Tophus - Wikipedia

    en.wikipedia.org/wiki/Tophus

    Tophi are pathognomonic for the disease gout. Most people with tophi have had previous attacks of acute arthritis, eventually leading to the formation of tophi. Chronic tophaceous gout is known as Harrison Syndrome. [1] Tophi form in the joints, cartilage, bones, and other places throughout the body.

  6. Purine metabolism - Wikipedia

    en.wikipedia.org/wiki/Purine_metabolism

    Symptoms can include gout, anaemia, epilepsy, delayed development, deafness, compulsive self-biting, kidney failure or stones, or loss of immunity. Purine metabolism can have imbalances that can arise from harmful nucleotide triphosphates incorporating into DNA and RNA which further lead to genetic disturbances and mutations, and as a result ...

  7. Demetrios Pepagomenos - Wikipedia

    en.wikipedia.org/wiki/Demetrios_Pepagomenos

    In his Σύνταγμα περὶ τῆς ποδάγρας, Pepagomenos considered gout a diathesis caused by a defective elimination of excreta. [3] Although Demetrios Pepagomenos is credited for providing a general description of gout, it was John Chumnus (utilizing Pepagomenos's work) who specifically established a proper diet for treating ...

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