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Agouti Mice These mice are genetically identical despite looking phenotypically different. The mouse on the left's mother was fed Bisphenol A (BPA) with a normal mouse diet and the mouse on the right's mother was fed BPA with a methyl-rich diet. The left mouse is yellow and obese, while the right mouse is brown and healthy.
Agouti-signaling protein is a protein that in humans is encoded by the ASIP gene. [5] [6] It is responsible for the distribution of melanin pigment in mammals.[7] [8] Agouti interacts with the melanocortin 1 receptor to determine whether the melanocyte (pigment cell) produces phaeomelanin (a red to yellow pigment), or eumelanin (a brown to black pigment). [9]
An agouti dog, also called wolf sable. In dogs, the agouti gene is associated with various coat colors and patterns. [10]The alleles at the A locus are related to the production of agouti-signaling protein (ASIP) and determine whether an animal expresses an agouti appearance and, by controlling the distribution of pigment in individual hairs, what type of agouti.
The Mouse Models of Human Cancer database (MMHCdb) is a unique, ... The first inbred strain, DBA (dilute brown agouti), was developed in 1909. [7]
This is an accepted version of this page This is the latest accepted revision, reviewed on 7 January 2025. Order of mammals Rodent Temporal range: Late Paleocene – recent PreꞒ Ꞓ O S D C P T J K Pg N Capybara Springhare Golden-mantled ground squirrel North American beaver House mouse Scientific classification Domain: Eukaryota Kingdom: Animalia Phylum: Chordata Class: Mammalia Mirorder ...
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The agouti (/ ə ˈ ɡ uː t iː / ⓘ, ə-GOO-tee) or common agouti is many of several rodent species of the genus Dasyprocta. They are native to Central America , northern and central South America , and the southern Lesser Antilles .