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A zoster vaccine is a vaccine that reduces the incidence of herpes zoster (shingles), a disease caused by reactivation of the varicella zoster virus, which is also responsible for chickenpox. [8] Shingles provokes a painful rash with blisters, and can be followed by chronic pain ( postherpetic neuralgia ), as well as other complications.
Adults 50 and older should get two doses of the shingles vaccine Shingrix. The doses should be separated by two or six months, the CDC says. ... chickenpox virus. Merck has sold a shingles vaccine ...
Varicella zoster virus is not the same as herpes simplex virus, although they both belong to the alpha subfamily of herpesviruses. [14] Shingles vaccines reduce the risk of shingles by 50 to 90%, depending on the vaccine used. [1] [15] Vaccination also decreases rates of postherpetic neuralgia, and, if shingles occurs, its severity. [1]
The herpes zoster vaccine is recommended for prevention in those over the age of 50. [2] HZO is the second most common manifestation of shingles, the first being involvement of skin of the thorax. [citation needed] Shingles affects up to one half million people in the United States per year, of which 10% to 25% is HZO. [1] [3]
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Shingles is prevented by immunizing against the causal virus, varicella zoster, using a zoster vaccine. Vaccination is recommended for adults 50 and older. Two versions of the vaccine are available, the live attenuated Zostavax (now discontinued in the US, essentially a larger-dose chickenpox vaccine) and the protein subunit Shingrix. [7]
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