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The albino laboratory mouse is an iconic model organism for scientific research in a variety of fields An SCID Intermediate coat colour Kept as a pet. The laboratory mouse or lab mouse is a small mammal of the order Rodentia which is bred and used for scientific research or feeders for certain pets.
By far the most popular laboratory rodent, the C57BL/6 mouse accounts for 1 ⁄ 2 to 5 ⁄ 6 of all rodents shipped to research laboratories from American suppliers. [1] Its overwhelming popularity is due largely to inertia: it has been widely used and widely studied, and therefore it is used even more. [1]
Laboratory mice typically belong to standardized inbred strains selected for the stability or clarity of specific harmful mutations. This allows research with laboratory mice to easily restrict genetic and biological variables, making them very useful model organisms in genetic and medicinal research. [85]
A dead mouse found in a cage in a clandestine Reedley laboratory is surrounded by decaying carcasses of mice that died previously in this photo taken by city code enforcement officers in April 2023.
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A report from Seton Hall University describes the suspension of a faculty member after lab mice were forced to live in "extremely dirty" conditions.
Many laboratory animals, including mice and rats, are chronically stressed which can also negatively affect research outcomes and the ability to accurately extrapolate findings to humans. [32] [33] Researchers have also noted that many studies involving mice, rats and other rodents are poorly designed, leading to questionable findings.
BALB/c is an albino, laboratory-bred strain of the house mouse from which a number of common substrains are derived. Now over 200 generations from New York in 1920, BALB/c mice are distributed globally, and are among the most widely used inbred strains used in animal experimentation.