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Cutis laxa [1] or pachydermatocele [2] is a group of rare connective tissue disorders in which the skin becomes inelastic and hangs loosely in folds. [ 3 ] Signs and symptoms
About 70% of perimenopausal women experience them and close to 80% of menopausal women get them as well, says Dr. Jewel Kling, associate director of women's health for Mayo Clinic in Arizona ...
In pathology, a contracture is a shortening of muscles, tendons, skin, and nearby soft tissues that causes the joints to shorten and become very stiff, preventing normal movement. [ 1 ] [ 2 ] A contracture is usually permanent, but less commonly can be temporary (such as in McArdle disease ), [ 3 ] or resolve over time but reoccur later in life ...
Collagenase clostridium histolyticum is an enzyme produced by the bacterium Clostridium histolyticum that dismantles collagen.It is used as a powder-and-solvent injection kit for the treatment of Dupuytren's contracture, a condition where the fingers bend towards the palm and cannot be fully straightened, and Peyronie's disease, a connective tissue disorder involving the growth of fibrous ...
Without sufficient oxygen, the tissue will die. [23] On a large scale, this can cause Volkmann's contracture in affected limbs, a permanent and irreversible process. [24] [25] [26] Other reported complications include neurological deficits of the affected limb, gangrene, and chronic regional pain syndrome. [27]
“When systemic and chronic inflammation accompanies these underlying diseases, it can affect multiple organ systems, manifesting as fatigue, muscle weakness, digestive disturbances, joint pain ...
The predominant clinical symptoms of wrinkly skin syndrome are wrinkled and inelastic skin over the face, backs of hands/fingers, tops of feet, and abdomen; delayed closure of the fontanelle (baby's soft spot), and increased palmar and plantar creases in the hands and feet, respectively.
Manhattan-based dermatologist Dr. Brendan Camp, M.D., said that toasted skin syndrome, officially known as erythema ab igne (EAI), is a "pattern of discoloration that occurs in areas of skin after ...