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2. Forensic DNA analysis - Wikipedia

   en.wikipedia.org/wiki/Forensic_DNA_analysis

   Developed in 1991, [10] DQ alpha testing was the first forensic DNA technique that utilized the polymerase chain reaction. [11] This technique allowed for the use of far fewer cells than RFLP analysis making it more useful for crime scenes that did not have the large amounts of DNA material that was previously required. [ 12 ]

3. Mitochondrial DNA - Wikipedia

   en.wikipedia.org/wiki/Mitochondrial_DNA

   Mitochondrial DNA is a small portion of the DNA contained in a eukaryotic cell; most of the DNA is in the cell nucleus, and, in plants and algae, the DNA also is found in plastids, such as chloroplasts. [3] Human mitochondrial DNA was the first significant part of the human genome to be sequenced. [4]

4. Cambridge Reference Sequence - Wikipedia

   en.wikipedia.org/wiki/Cambridge_Reference_Sequence

   The Cambridge Reference Sequence (CRS) for human mitochondrial DNA was first announced in 1981. [ 2 ] A group led by Fred Sanger at the University of Cambridge had sequenced the mitochondrial genome of one woman of European descent [ 3 ] during the 1970s, determining it to have a length of 16,569 base pairs (0.0006% of the nuclear human genome ...

5. Genealogical DNA test - Wikipedia

   en.wikipedia.org/wiki/Genealogical_DNA_test

   The mitochondrion is a component of a human cell, and contains its own DNA. Mitochondrial DNA usually has 16,569 base pairs (the number can vary slightly depending on addition or deletion mutations) [24] and is much smaller than the human genome DNA which has 3.2 billion base pairs. Mitochondrial DNA is transmitted from mother to child, as it ...

6. Human mitochondrial genetics - Wikipedia

   en.wikipedia.org/wiki/Human_mitochondrial_genetics

   The human mitochondrial genome is the entirety of hereditary information contained in human mitochondria. Mitochondria are small structures in cells that generate energy for the cell to use, and are hence referred to as the "powerhouses" of the cell. Mitochondrial DNA (mtDNA) is not transmitted through nuclear DNA (nDNA).

7. Haplogroup K (mtDNA) - Wikipedia

   en.wikipedia.org/wiki/Haplogroup_K_(mtDNA)

   Haplogroup K, formerly Haplogroup UK, is a human mitochondrial DNA (mtDNA) haplogroup. It is defined by the HVR1 mutations 16224C and 16311C. It is now known that K is a subclade of U8 .

8. POLRMT - Wikipedia

   en.wikipedia.org/wiki/POLRMT

   DNA-directed RNA polymerase, mitochondrial is an enzyme that in humans is encoded by the POLRMT gene. [5] [6] Function ... (Human DNA-directed RNA polymerase, ...

9. Douglas C. Wallace - Wikipedia

   en.wikipedia.org/wiki/Douglas_C._Wallace

   Wallace is a pioneer in the study of mitochondrial DNA.Wallace and his colleagues introduced human mitochondrial genetics into the field of molecular genetics. [10] In 1975, for the first time ever, Wallace could associate a genetic disorder with the mitochondrial DNA region (resistance to chloramphenicol) [11] and in 1990 he described a mitochondrial DNA mutation as the cause of a particular ...