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This breed of rat was first produced by the Sprague Dawley farms (later to become the Sprague Dawley Animal Company) in Madison, Wisconsin, in 1925. The name was originally hyphenated, although the brand styling today (Sprague Dawley, the trademark used by Inotiv) is not. The average litter size of the Sprague Dawley rat is 11.0. [29]
The fancy rat (Rattus norvegicus domestica) is the domesticated form of Rattus norvegicus, the brown rat, [1] and the most common species of rat kept as a pet.The name fancy rat derives from the use of the adjective fancy for a hobby, also seen in "animal fancy", a hobby involving the appreciation, promotion, or breeding of pet or domestic animals.
Even though SHR is usually considered to be a purely pathological model, the strain exhibit interesting compensatory abilities. For example, kidneys transplanted from SHR to a hypertensive recipient retain better morphology than kidneys transplanted from Brown Norway, [6] demonstrating a pathological adaptation to high blood pressure.
Laboratory rat#Sprague Dawley rat To a section : This is a redirect from a topic that does not have its own page to a section of a page on the subject. For redirects to embedded anchors on a page, use {{ R to anchor }} instead .
Intentionally bred albinistic strains of some animal species are commonly used as model organisms in biomedical research and also as pets. Examples include the BALB/c mouse and Wistar and Sprague Dawley rat strains, laboratory rabbits and ferrets. [39]
For example, in one experiment, male Sprague-Dawley rats were given either a low fat or a high fat diet, with the high fat diet containing 35% more fat than the low fat diet. The results of the study illustrate that the high fat diet rats had a higher adiposity index than the low fat diet rats.
Harlan UK Ltd. is the British arm of Harlan Sprague Dawley Inc. It has an annual turnover of £6.6 million, according to the British Union for the Abolition of Vivisection (BUAV). [6] The company supplies marmosets, beagles, cats, rabbits, guinea pigs, rats, mice, gerbils, and hamsters, as well as hybrid, mutant, and transgenic animals.
Several studies have examined the remote control of rats using micro-electrodes implanted into their brains and rely on stimulating the reward centre of the rat. Three electrodes are implanted; two in the ventral posterolateral nucleus of the thalamus which conveys facial sensory information from the left and right whiskers, and a third in the medial forebrain bundle which is involved in the ...