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In principle, crystal formation can happen anywhere in the body. Well-known places are excretory organs where concentrations get high easily, like in the biliary and urinary tracts , but crystalline structures are also formed in intracellular and extracellular spaces of tissues, like within the arterial wall in atherosclerosis .
In this advanced stage of gout, hardened deposits of uric acid crystals form around the joints and sometimes areas of the body like the kidneys. ... can cause gout in the feet or other lower-body ...
Gout (/ ɡ aʊ t / GOWT [7]) is a form of inflammatory arthritis characterized by recurrent attacks of pain in a red, tender, hot, and swollen joint, [2] [8] caused by the deposition of needle-like crystals of uric acid known as monosodium urate crystals. [9] Pain typically comes on rapidly, reaching maximal intensity in less than 12 hours. [5]
Calcium pyrophosphate dihydrate (CPPD) crystal deposition disease, also known as pseudogout and pyrophosphate arthropathy, is a rheumatologic disease which is thought to be secondary to abnormal accumulation of calcium pyrophosphate dihydrate crystals within joint soft tissues. [1]
What causes gout? The condition is caused by a buildup of uric acid in the body. ... Uric acid forms crystals around joints in the body, most commonly in the big toe or knee, but can be found in ...
Analysis of a sample of synovial fluid to look for signs of an infection (infectious arthritis) or uric acid crystals (gout) Imaging tests, such as X-rays or MRI scans, to evaluate the condition ...
When uric acid levels and gout symptoms cannot be controlled with standard gout medicines that decrease the production of uric acid (e.g., allopurinol, febuxostat) or increase uric acid elimination from the body through the kidneys (e.g., probenecid), this can be referred to as refractory chronic gout (RCG). [3]
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