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A cancer cluster is a disease cluster in which a high number of cancer cases occurs in a group of people in a particular geographic area over a limited period of time. [ 1 ] Historical examples of work-related cancer clusters are well documented in the medical literature.
The cancer stem cell model asserts that within a population of tumour cells, there is only a small subset of cells that are tumourigenic (able to form tumours). These cells are termed cancer stem cells (CSCs), and are marked by the ability to both self-renew and differentiate into non-tumourigenic progeny. The CSC model posits that the ...
Collecting duct carcinoma (CDC) is a type of kidney cancer that originates in the papillary duct of the kidney. It is rare, accounting for 1-3% of all kidney cancers. [ 2 ] It is also recently described; a 2002 review found just 40 case reports worldwide. [ 3 ]
Transmissible cancers follow the general pattern of cancer spread, starting with the growth of primary cancer cells at tumor sites followed by invasion of surrounding tissue and subsequent spread throughout the organism. [5] The main hurdles for surviving cells of a successful spread to a new host are histocompatibility barriers.
State cancer registries monitor cancer trends, determine cancer patterns, direct planning and evaluation of cancer control programs, help set priorities for allocating health resources, promote research, and provide information on cancer incidence. The data collected helps public health professionals understand and address the cancer burden.
The term is used for two distinct concepts, often conflated: mutagen signatures and tumor signatures. Its original use, mutagen signature, referred to a pattern of mutations made in the laboratory by a known mutagen and not made by other mutagens – unique to the mutagen as a human signature is unique to the signer.
But brain cancer was the most common cause of cancer deaths among youths in 2021, according to the CDC report. Death rates for brain cancer that year were 23% higher than for leukemia, and more ...
The Cancer Genome Atlas (TCGA) is a project to catalogue the genomic alterations responsible for cancer using genome sequencing and bioinformatics. [1] [2] The overarching goal was to apply high-throughput genome analysis techniques to improve the ability to diagnose, treat, and prevent cancer through a better understanding of the genetic basis of the disease.