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  2. Kavalactone - Wikipedia

    en.wikipedia.org/wiki/Kavalactone

    Kavalactones are a class of lactone compounds found in kava roots and Alpinia zerumbet (shell ginger). [1] and in several Gymnopilus, Phellinus and Inonotus fungi. [2] Some kavalactones are bioactive. They are responsible for the psychoactive, analgesic, euphoric and sedative effects of kava. [3] [4]

  3. Kava - Wikipedia

    en.wikipedia.org/wiki/Kava

    Kava or kava kava (Piper methysticum: Latin 'pepper' and Latinized Greek 'intoxicating') is a plant in the pepper family, native to the Pacific Islands. [1] The name kava is from Tongan and Marquesan , meaning 'bitter.’ [ 1 ] Other names for kava include ʻawa ( Hawaiʻi ), [ 2 ] ʻava ( Samoa ), yaqona or yagona ( Fiji ), [ 3 ] sakau ...

  4. Desmethoxyyangonin - Wikipedia

    en.wikipedia.org/wiki/Desmethoxyyangonin

    This, along with several other catecholamines, may be responsible for the purported attention-promoting effects of kava. Unlike the other major kavalactones, desmethoxyyangonin does not appear to act as a GABA A receptor positive allosteric modulator .

  5. Kavain - Wikipedia

    en.wikipedia.org/wiki/Kavain

    Kavain has anticonvulsive properties, attenuating vascular smooth muscle contraction through interactions with voltage-dependent Na + and Ca 2+ channels. [1] How this effect is mediated, and to what extent this mechanism is involved in the anxiolytic and analgesic effects of kavalactones on the central nervous system, is unknown.

  6. Methysticin - Wikipedia

    en.wikipedia.org/wiki/Methysticin

    Methysticin is one of the six major kavalactones found in the kava plant. [1] Research suggests that methysticin and the related compound dihydromethysticin have CYP1A1 inducing effects which may be responsible for their toxicity. [2]

  7. List of substances used in rituals - Wikipedia

    en.wikipedia.org/wiki/List_of_substances_used_in...

    Kava: Piper methysticum: Root: [63] 3-20% kavalactones: Depressant: Kava cultures are the religious and cultural traditions of western Oceania which consume kava. Khat: Catha edulis: Leaf: [64] cathine up to 14% [65] [66] Stimulant: For centuries, religious leaders have consumed the leaves to stay awake during long nights of prayer. [67] Kratom ...

  8. List of herbs with known adverse effects - Wikipedia

    en.wikipedia.org/wiki/List_of_herbs_with_known...

    Papaya extract Carica papaya: Warfarin Damage to GI tract mucous membranes [3] Kava: kava-kava Piper methysticum: Sedatives, sleeping pills, antipsychotics, alcohol [15] Milkvetch: Astragalus: Astragalus may interact with medications that suppress the immune system, such as cyclophosphamide. [24] It may also affect blood sugar levels and blood ...

  9. Dosage (pharmacology) - Wikipedia

    en.wikipedia.org/wiki/Dosage_(pharmacology)

    Dosage typically includes information on the number of doses, intervals between administrations, and the overall treatment period. [3] For example, a dosage might be described as "200 mg twice daily for two weeks," where 200 mg represents the individual dose, twice daily indicates the frequency, and two weeks specifies the duration of treatment.

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