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  2. Nortriptyline - Wikipedia

    en.wikipedia.org/wiki/Nortriptyline

    Nortriptyline is an active metabolite of amitriptyline by demethylation in the liver. Chemically, it is a secondary amine dibenzocycloheptene and pharmacologically it is classed as a first-generation antidepressant. [36] Nortriptyline may also have a sleep-improving effect due to antagonism of the H 1 and 5-HT 2A receptors. [37]

  3. Amitriptyline - Wikipedia

    en.wikipedia.org/wiki/Amitriptyline

    On the other hand, cytochrome P450 inducers such as carbamazepine and St. John's Wort decrease the levels of both amitriptyline and nortriptyline [71] [76] Oral contraceptives may increase the blood level of amitriptyline by as high as 90%. [77] Valproate moderately increases the levels of amitriptyline and nortriptyline through an unclear ...

  4. Your Guide to the 6 Most Common Types of Depression ... - AOL

    www.aol.com/6-types-depression-medications...

    Amitriptyline, sold under the name Elavil, is a tricyclic antidepressant used to treat depression, especially when other medications aren’t effective. It’s also used to treat certain forms of ...

  5. Protriptyline - Wikipedia

    en.wikipedia.org/wiki/Protriptyline

    Other secondary amine TCAs include desipramine and nortriptyline. [ 26 ] [ 27 ] The chemical name of protriptyline is 3-(5 H -dibenzo[ a , d ][7]annulen-5-yl)- N -methylpropan-1-amine and its free base form has a chemical formula of C 19 H 21 N 1 with a molecular weight of 263.377 g/mol. [ 28 ] The drug is used commercially mostly as the ...

  6. Doctors Say This Viral "Sleep Rule" Actually Works - AOL

    www.aol.com/lifestyle/doctors-viral-sleep-rule...

    TikTok is filled with tips and tricks — some legitimate, many not — to help you sleep better. One of the latest encourages people to follow a 10-3-2-1-0 sleep rule, which is actually not just ...

  7. Serotonin–norepinephrine–dopamine reuptake inhibitor

    en.wikipedia.org/wiki/Serotonin–norepinephrine...

    The TCAs such as imipramine and amitriptyline typically prevent the reuptake of serotonin or norepinephine. It is the histaminiergic (H 1), muscarinic acetylcholinergic (M 1), and alpha adrenergic (α 1) blockade that is responsible for the side-effects of TCAs. These include somnolence and lethargy, anticholinergic side-effects, and hypotension.

  8. Tricyclic antidepressant - Wikipedia

    en.wikipedia.org/wiki/Tricyclic_antidepressant

    [54] [55] [56] They are the dibenzazepines (imipramine, desipramine, clomipramine, trimipramine, lofepramine) and the dibenzocycloheptadienes (amitriptyline, nortriptyline, protriptyline, butriptyline). [54] [55] Minor TCA groups based on ring system include the dibenzoxepins , the dibenzothiepines , and the dibenzoxazepines .

  9. Sleep Doctors Share the 1 Tip That's Changed Their Lives - AOL

    www.aol.com/lifestyle/sleep-doctors-share-1-tip...

    Even though we spend roughly a third of our lives doing it, sleep doesn’t always come easily. More than one in three adults in the U.S. don’t get enough sleep, so there’s a good chance you ...

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