Search results
Results from the WOW.Com Content Network
The Hofmann rearrangement (Hofmann degradation) is the organic reaction of a primary amide to a primary amine with one less carbon atom. [ 1 ] [ 2 ] [ 3 ] The reaction involves oxidation of the nitrogen followed by rearrangement of the carbonyl and nitrogen to give an isocyanate intermediate.
The Hofmann–Martius rearrangement in organic chemistry is a rearrangement reaction converting an N-alkylated aniline to the corresponding ortho and / or para aryl-alkylated aniline. The reaction requires heat, and the catalyst is an acid like hydrochloric acid .
The Hofmann rearrangement is a decarbonylation reaction whereby an amide is converted to an amine by way of an isocyanate intermediate. It is usually carried out under strongly basic conditions. It is usually carried out under strongly basic conditions.
The least stable alkene (the one with the fewest substituents on the carbons of the double bond), called the Hofmann product, is formed. This tendency, known as the Hofmann alkene synthesis rule , is in contrast to usual elimination reactions, where Zaitsev's rule predicts the formation of the most stable alkene.
Nebraska Gov. Jim Pillen is facing backlash after comments he made about the Chinese nationality of a reporter whose story cited environmental concerns at farms owned by the governor.
In organic chemistry, a rearrangement reaction is a broad class of organic reactions where the carbon skeleton of a molecule is rearranged to give a structural isomer of the original molecule. [1] Often a substituent moves from one atom to another atom in the same molecule, hence these reactions are usually intramolecular.
A video supposedly showing a 'ballot mule' stuffing a ballot box in Nebraska instead recorded a man memorializing his first vote for president.
R. P. Deshpande and U. R. Nayak [37] reported that the Hofmann–Löffler–Freytag reaction is applicable to the synthesis of pyrrolidines containing a longifolene nucleus, e.g. 62. An outstanding application of the Hofmann–Löffler–Freytag reaction is found in the preparation of the steroidal alkaloid derivatives. J.