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Such a quadruplex is described as tetramolecular, reflecting the requirement of four separate strands. The term G4 DNA was originally reserved for these tetramolecular structures that might play a role in meiosis. [5] However, as currently used in molecular biology, the term G4 can mean G-quadruplexes of any molecularity.
In the context of a biological system, bifurcation theory describes how small changes in an input parameter can cause a bifurcation or qualitative change in the behavior of the system. The ability to make dramatic change in system output is often essential to organism function, and bifurcations are therefore ubiquitous in biological networks ...
Pierre Janet was one of the first to use the concept in psychology. Mental operations have been investigated at a developmental level by Jean Piaget, and from a psychometric perspective by J. P. Guilford. There is also a cognitive approach to the subject, as well as a systems view of it.
Health psychology examines the reciprocal influences of biology, psychology, behavioral, and social factors on health and illness. One application of the biopsychosocial model within health and medicine relates to pain, such that several factors outside an individual's health may affect their perception of pain.
DNAzyme research for the treatment of cancer is also underway. The development of a 10-23 DNAzyme that can block the expression of IGF-I (Insulin-like growth factor I, a contributor to normal cell growth as well as tumorigenesis) by targeting its mRNA could be useful for blocking the secretion of IGF-I from prostate storm primary cells ...
The PASS theory provides the theoretical framework for a measurement instrument called the Das-Naglieri Cognitive Assessment System (CAS), published in 1997. [6] This test, now in a Second Edition (CAS2; 2014, Naglieri, Das & Gold-stein) is designed to provide an assessment of intellectual functioning redefined as four brain-based cognitive processes (Planning, Attention, Simultaneous and ...
Salience bias, like all other cognitive biases, is an applicable concept to various disciplines. For example, cognitive psychology investigates cognitive functions and processes, such as perception, attention, memory, problem solving, and decision making, all of which could be influenced by salience bias. Salience bias acts to combat cognitive ...
As an example, weighted gene co-expression network analysis uses Pearson correlation to analyze linked gene expression and understand genetics at a systems level. [50] Another measure of correlation is linkage disequilibrium. Linkage disequilibrium describes the non-random association of genetic sequences among loci in a given chromosome. [51]