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o-Toluidine is absorbed through inhalation and dermal contact as well as from the gastrointestinal tract. [19] [13] [20] [21]The metabolism of o-toluidine involves many competing activating and deactivating pathways, including N-acetylation, N-oxidation, and N-hydroxylation, and ring oxidation.
2-Tolidine (orthotolidine, o-tolidine; not to be confused with o-toluidine) is an organic compound with the chemical formula (C 6 H 4 (CH 3)NH 2) 2. Several isomers are known; the 3-tolidine derivative is also important commercially. It is a colorless compound although commercial samples are often colored. It is slightly soluble in water.
There are three isomers of toluidine, which are organic compounds discovered and named by James Sheridan Muspratt and August Wilhelm von Hofmann in 1845. [1] These isomers are o-toluidine, m-toluidine, and p-toluidine, with the prefixed letter abbreviating, respectively, ortho; meta; and para.
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On a chilly day, there’s nothing more comforting than curling up under a cozy blanket with a warm cup of tea. But tea offers much more than just comfort and hydration in cold weather.
Therapy can include the use of zinc supplements to reduce the duration of diarrhea in infants and children under the age of 5. [1] Use of oral rehydration therapy has been estimated to decrease the risk of death from diarrhea by up to 93%. [2] Side effects may include vomiting, high blood sodium, or high blood potassium. [1]
The use of organ bath preparations for the measurement of physiological tissue responses to drug concentrations allows the generation of dose response curves. This in turn allows the quantification of a drug's pharmacological profile in the tissue in question, such as the calculation of the drug's EC50 , IC50 , and Hill coefficient .