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A germ layer is a primary layer of cells that forms during embryonic development. [1] The three germ layers in vertebrates are particularly pronounced; however, all eumetazoans ( animals that are sister taxa to the sponges ) produce two or three primary germ layers.
Both the embryoblast and the trophoblast will turn into two sub-layers. [11] The inner cells will turn into the hypoblast layer, which will surround the other layer, called the epiblast, and these layers will form the embryonic disc that will develop into the embryo. [10] [11]
As the number of cells grows from 16 to between 40 and 150, the blastocyst differentiates into two layers, an outer sphere of cells called the trophoblast and an inner cell mass called the embryoblast. The spherical outer cell layer (trophoblast), after implantation in the wall of the uterus, further differentiates and grows to form the placenta.
These three germ layers are the ectoderm (outer layer), mesoderm (middle layer), and endoderm (inner layer). [3] [4] In diploblastic organisms, such as Cnidaria and Ctenophora, the gastrula has only ectoderm and endoderm. The two layers are also sometimes referred to as the hypoblast and epiblast. [5] Sponges do not go through the gastrula stage.
During implantation the blastocyst, which contains the inner cell mass, undergoes cellular differentiation into the two layers of the bilaminar embryonic disc. One of which is the epiblast, also known as the primitive ectoderm. The epiblast is the outer layer of the bilaminar embryonic disc and consists of columnar cells.
The mesoderm is the middle layer of the three germ layers, between the outer ectoderm and inner endoderm. During the third week of embryonic development the lateral plate mesoderm splits into two layers forming the intraembryonic coelom .
The ectoderm is one of the three primary germ layers formed in early embryonic development. It is the outermost layer, and is superficial to the mesoderm (the middle layer) and endoderm (the innermost layer). [1] It emerges and originates from the outer layer of germ cells.
The germ layers are referred to as the ectoderm, mesoderm and endoderm. In diploblastic animals only the ectoderm and the endoderm are present. [8] * Among different animals, different combinations of the following processes occur to place the cells in the interior of the embryo: Epiboly – expansion of one cell sheet over other cells [9]
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