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Testosterone is the primary male sex hormone and androgen in males. [3] In humans, testosterone plays a key role in the development of male reproductive tissues such as testicles and prostate, as well as promoting secondary sexual characteristics such as increased muscle and bone mass, and the growth of body hair.
Conversely, “with too much testosterone, women often have acne, too much hair on the body, hair loss on the head, high blood pressure, elevated cholesterol, skipped cycles, or problems ...
The elimination half-life of DHT in the body (53 minutes) is longer than that of testosterone (34 minutes), and this may account for some of the difference in their potency. [51] A study of transdermal (patches) DHT and testosterone treatment reported terminal half-lives of 2.83 hours and 1.29 hours, respectively. [52]
Normal function of the androgen receptor. Testosterone (T) enters the cell and, if 5-alpha-reductase is present, is converted into dihydrotestosterone (DHT). Upon steroid binding, the androgen receptor (AR) undergoes a conformational change and releases heat-shock proteins (hsps). Phosphorylation (P) occurs before or after steroid binding.
Notably, conditions including diabetes, kidney and liver diseases, recent weight increases, thyroid disorders, and even sleep apnea can all cause a decrease in testosterone, and thus libido, and ...
Testosterone is an essential hormone for both men and women, playing an important role in muscle growth and cognitive function. Low levels of the hormone can lead to changes in mood, cognition and ...
Testosterone is a medication and naturally occurring steroid hormone. [9] It is used to treat male hypogonadism, gender dysphoria, and certain types of breast cancer. [9] [10] It may also be used to increase athletic ability in the form of doping. [9]
This is an accepted version of this page This is the latest accepted revision, reviewed on 3 March 2025. Polycyclic organic compound having sterane as a core structure This article is about the family of polycyclic compounds. For the drugs, also used as performance-enhancing substances, see Anabolic steroid. For the scientific journal, see Steroids (journal). For the Death Grips EP, see ...