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  2. Protein pKa calculations - Wikipedia

    en.wikipedia.org/wiki/Protein_pKa_calculations

    The pK a values of an amino acid side chain in solution is typically inferred from the pK a values of model compounds (compounds that are similar to the side chains of amino acids). See Amino acid for the pK a values of all amino acid side chains inferred in such a way. There are also numerous experimental studies that have yielded such values ...

  3. Acid dissociation constant - Wikipedia

    en.wikipedia.org/wiki/Acid_dissociation_constant

    The acid dissociation constant for an acid is a direct consequence of the underlying thermodynamics of the dissociation reaction; the pK a value is directly proportional to the standard Gibbs free energy change for the reaction.

  4. Proteinogenic amino acid - Wikipedia

    en.wikipedia.org/wiki/Proteinogenic_amino_acid

    The table below lists the abundance of amino acids in E.coli cells and the metabolic cost (ATP) for synthesis of the amino acids. Negative numbers indicate the metabolic processes are energy favorable and do not cost net ATP of the cell. [12] The abundance of amino acids includes amino acids in free form and in polymerization form (proteins).

  5. Amino acid - Wikipedia

    en.wikipedia.org/wiki/Amino_acid

    3.1 Table of standard amino acid abbreviations and properties. ... This peptide is synthesized in two steps from free amino acids. [134] In the first step, ...

  6. Lysine - Wikipedia

    en.wikipedia.org/wiki/Lysine

    Lysine (symbol Lys or K) [2] is an α-amino acid that is a precursor to many proteins.Lysine contains an α-amino group (which is in the protonated −NH + 3 form when the lysine is dissolved in water at physiological pH), an α-carboxylic acid group (which is in the deprotonated −COO − form when the lysine is dissolved in water at physiological pH), and a side chain (CH 2) 4 NH 2 (which ...

  7. Glycine - Wikipedia

    en.wikipedia.org/wiki/Glycine

    Glycine (symbol Gly or G; [6] / ˈ ɡ l aɪ s iː n / ⓘ) [7] is an amino acid that has a single hydrogen atom as its side chain. It is the simplest stable amino acid (carbamic acid is unstable). Glycine is one of the proteinogenic amino acids. It is encoded by all the codons starting with GG (GGU, GGC, GGA, GGG). [8]

  8. Alanine - Wikipedia

    en.wikipedia.org/wiki/Alanine

    Alanine is an aliphatic amino acid, because the side-chain connected to the α-carbon atom is a methyl group (-CH 3). Alanine is the simplest α-amino acid after glycine . The methyl side-chain of alanine is non-reactive and is therefore hardly ever directly involved in protein function. [ 12 ]

  9. Glutamic acid - Wikipedia

    en.wikipedia.org/wiki/Glutamic_acid

    Glutamic acid (symbol Glu or E; [4] the anionic form is known as glutamate) is an α-amino acid that is used by almost all living beings in the biosynthesis of proteins. It is a non-essential nutrient for humans, meaning that the human body can synthesize enough for its use.