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  2. Duplicated ureter - Wikipedia

    en.wikipedia.org/wiki/Duplicated_ureter

    Duplicated ureter or duplex collecting system is a congenital condition in which the ureteric bud, the embryological origin of the ureter, splits (or arises twice), resulting in two ureters draining a single kidney. It is the most common renal abnormality, occurring in approximately 1% of the population.

  3. List of drugs granted breakthrough therapy designation

    en.wikipedia.org/wiki/List_of_drugs_granted...

    non–central nervous system manifestations of acid sphingomyelinase deficiency: Spesolimab: Boehringer Ingelheim: generalized pustular psoriasis: Futibatinib: Taiho Oncology: intrahepatic cholangiocarcinoma with FGFR2 gene fusions or other rearrangements Teclistamab: Janssen: multiple myeloma: Teplizumab: Provention Bio

  4. Eculizumab - Wikipedia

    en.wikipedia.org/wiki/Eculizumab

    Health Canada approved it in 2009, to treat paroxysmal nocturnal hemoglobinuria and in 2013, as the only drug to treat atypical hemolytic uremic syndrome. [ 25 ] Eculizumab was approved by the FDA for the treatment of adults with neuromyelitis optica spectrum disorder who are anti-aquaporin-4 (AQP4) antibody positive in 2019, based on the ...

  5. Muromonab-CD3 - Wikipedia

    en.wikipedia.org/wiki/Muromonab-CD3

    Muromonab-CD3 was approved by the U.S. Food and Drug Administration (FDA) in 1986, [5] making it the first monoclonal antibody to be approved anywhere as a drug for humans. In the European Communities , it is the first drug to be approved under the directive 87/22/EWG, a precursor of the European Medicines Agency (EMA) centralised approval ...

  6. US FDA approves Novartis' kidney disease drug - AOL

    www.aol.com/news/us-fda-approves-novartis-kidney...

    (Reuters) -The U.S. Food and Drug Administration has approved the use of Novartis' drug to reduce excess protein in the urine of patients with a type of kidney disease, the health regulator's ...

  7. List of drugs known for off-label use - Wikipedia

    en.wikipedia.org/wiki/List_of_drugs_known_for...

    Misoprostol is approved for medical abortion regimens when administered at the office, but clinicians often give abortion patients the drug to be taken at home. [15] Modafinil is a central nervous system (CNS) stimulant medication used to treat sleepiness due to narcolepsy, shift work sleep disorder, and obstructive sleep apnea. It is often ...

  8. New hope for kidney cancer treatment using existing drugs - AOL

    www.aol.com/hope-kidney-cancer-treatment-using...

    The findings suggest IL1B macrophages could be a promising therapeutic target to treat kidney cancer, given this cell type has already been targeted using existing drugs that prevent lung cancer.

  9. Weight-loss surgery may preserve kidney health more ... - AOL

    www.aol.com/weight-loss-surgery-may-preserve...

    People with type 2 diabetes and obesity who develop kidney disease may benefit more from bariatric surgery than from GLP-1 drugs when it comes to preserving kidney function, a new study finds.

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