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Losing working memory has been cited as being the primary reason for a decline in a variety of cognitive tasks due to aging. These tasks include long-term memory, problem solving, decision making, and language. [31] Working memory involves the manipulation of information that is being obtained, and then using this information to complete a task.
This is an accepted version of this page This is the latest accepted revision, reviewed on 10 February 2025. Long-term brain disorders causing impaired memory, thinking and behavior This article is about the cognitive disorder. For other uses, see Dementia (disambiguation). "Senile" and "Demented" redirect here. For other uses, see Senile (disambiguation) and Demented (disambiguation). Medical ...
The difference in memory between normal aging and a memory disorder is the amount of beta-amyloid deposits, hippocampal neurofibrillary tangles, or amyloid plaques in the cortex. If there is an increased amount, memory connections become blocked, memory functions decrease much more than what is normal for that age and a memory disorder is ...
New research published in Neurology found that cognitively healthy people who self-reported memory problems had early signs of Alzheimer’s disease, such as higher tau tangles, in their brains.
A 46% decrease in spine number and spine density has been reported in humans older than 50 compared with younger individuals. [12] An electron microscopy study in monkeys reported a 50% loss in spines on the apical dendritic tufts of pyramidal cells in prefrontal cortex of old animals (27–32 years old) compared with young ones (6–9 years ...
Due to the emphasis shifting to the earlier diagnosis of dementia, more people are assessed who report memory problems. In turn this also leads diagnosing more people who might have MCI which is a risk factor for dementia. [24] [25] Globally, approximately 16% of the population over the age of 70 experiences some type of MCI. [medical citation ...
Alzheimer's disease (AD) is a neurodegenerative disease that usually starts slowly and progressively worsens. [2] It is the cause of 60–70% of cases of dementia. [2] [15] The most common early symptom is difficulty in remembering recent events. [1]
Difficulty creating recent term memories is called anterograde amnesia and is caused by damage to the hippocampus part of the brain, which is a major part of the memory process. [8] Retrograde amnesia is also caused by damage to the hippocampus, but the memories that were encoded or in the process of being encoded in long-term memory are erased [8]
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