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Side effects of selegiline occurring more often than with placebo include insomnia, dry mouth, dizziness, anxiety, abnormal dreams, and application site reactions (with the patch form), among others. [ 24 ] [ 25 ] [ 27 ] [ 4 ] [ 8 ] At high doses, selegiline has the potential for dangerous food and drug interactions , such as tyramine -related ...
Selank has an advantage over traditional anxiety treatments, such as benzodiazepines, as it has no sedating or negative cognitive side effects and no associated addiction or withdrawal problems. [citation needed] Selank is closely related to another nootropic drug, Semax, also developed by the Institute of Molecular Genetics in Russia. This ...
This supplement helps support cognitive function and may even reduce symptoms of depression and anxiety. The supplement's two main ingredients, eicosapentaenoic acid (EPA) and docosahexaenoic acid ...
The most significant risk associated with the use of MAOIs is the potential for drug interactions with over-the-counter, prescription, or illegally obtained medications, and some dietary supplements (e.g., St. John's wort or tryptophan). It is vital that a doctor supervise such combinations to avoid adverse reactions.
Meprobamate—marketed as Miltown by Wallace Laboratories and Equanil by Wyeth, among others—is a carbamate derivative used as an anxiolytic drug. It was the best-selling minor tranquilizer for a time, but has largely been replaced by the benzodiazepines due to their wider therapeutic index (lower risk of toxicity at therapeutically prescribed doses) and lower incidence of serious side effects.
[4] [7] More specifically, tranylcypromine acts as nonselective and irreversible inhibitor of the enzyme monoamine oxidase (MAO). [4] [7] It is used as an antidepressant and anxiolytic agent in the clinical treatment of mood and anxiety disorders, respectively. It is also effective in the treatment of ADHD. [8] [9]
Tianeptine has antidepressant and anxiolytic effects [13] with a relative lack of sedative, anticholinergic, and cardiovascular side effects. [ 10 ] [ 14 ] It has been found to act as an atypical agonist of the μ-opioid receptor with clinically negligible effects on the δ- and κ-opioid receptors .
Common adverse effects of bupropion with the greatest difference from placebo are dry mouth, nausea, constipation, insomnia, anxiety, tremor, and excessive sweating. [10] [11] Raised blood pressure is notable. [23] Rare but serious side effects include seizures, [10] [11] liver toxicity, [24] psychosis, [25] and risk of overdose. [26]
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