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Parkinsonism is a clinical syndrome characterized by the four motor symptoms found in Parkinson's disease: tremor, bradykinesia (slowed movements), rigidity, and postural instability. [1] [2] Parkinsonism gait problems can lead to falls and serious physical injuries. Other common symptoms include:
Furthermore, the gold-standard treatment varies with the disease state. People with Parkinson's, therefore, often must take a variety of medications to manage the disease's symptoms. [1] Several medications currently in development seek to better address motor fluctuations and nonmotor symptoms of PD.
The four cardinal motor symptoms of Parkinson's—bradykinesia (slowed movements), postural instability, rigidity, and tremor—are called parkinsonism. [9] [10] These four symptoms are not exclusive to Parkinson's and can occur in many other conditions, [11] [12] including HIV infection and recreational drug use.
Parkinson's Disease causes constipation and gastric dysmotility that is severe enough to endanger comfort and even health. [26] A factor in this is the appearance of Lewy bodies and Lewy neurites even before these affect the functioning of the substantia nigra in the neurons in the enteric nervous system that control gut functions.
This is a general list of long-term side effects associated with Antipsychotic (neuroleptic) medication.. Many patients will not develop these side effects, although there is still a significant possibility of risks associated with Antipsychotic usage.
Veronica Brown lived with chronic fatigue, depression, and anxiety for over 10 years before she learned they were early signs of Parkinson's disease. Here's how she found relief after diagnosis.
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