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1 Inhalational anesthetic agents. 2 Bronchodilators. 3 Anti-hypertensives. 4 Anti-inflammatories. ... A list of drugs or therapeutic agents administered via inhalation.
An inhalational anesthetic is a chemical compound possessing general anesthetic properties that is delivered via inhalation. They are administered through a face mask, laryngeal mask airway or tracheal tube connected to an anesthetic vaporiser and an anesthetic delivery system .
It is only recommended in those who have a normal level of consciousness and stable blood pressure and heart rate. [4] It is classified as a volatile anaesthetic. [4] It was first made in 1948 by William T. Miller and came into medical use in the 1960s. [7] It was used as a general anesthetic from its introduction in 1960 until the late 1970s. [8]
The Meyer-Overton correlation for anaesthetics. A nonspecific mechanism of general anaesthetic action was first proposed by Emil Harless and Ernst von Bibra in 1847. [9] They suggested that general anaesthetics may act by dissolving in the fatty fraction of brain cells and removing fatty constituents from them, thus changing activity of brain cells and inducing anaesthesia.
Sevoflurane is an inhaled anesthetic that is often used to induce and maintain anesthesia in children for surgery. [17] During the process of awakening from the medication, it has been associated with a high incidence (>30%) of agitation and delirium in preschool children undergoing minor noninvasive surgery. [ 17 ]
MAC is inversely related to potency, i.e. high MAC equals low potency. The hypothesis correlates lipid solubility of an anaesthetic agent with potency (1/MAC) and suggests that onset of anaesthesia occurs when sufficient molecules of the anaesthetic agent have dissolved in the cell's lipid membranes, resulting in anaesthesia.
This seems to be especially problematic in dental anesthesia. [25] Like all the potent inhalational anaesthetic agents, it is a potent trigger for malignant hyperthermia. [5] Similarly, in common with the other potent inhalational agents, it relaxes uterine smooth muscle and this may increase blood loss during delivery or termination of ...
Agent concentration measurement: anaesthetic machines typically have monitors to measure the percentage of inhalational anaesthetic agents used as well as exhalation concentrations. These monitors include measuring oxygen , carbon dioxide , and inhalational anaesthetics (e.g., nitrous oxide , isoflurane ).