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The Geography of Atlanta encompasses 132.4 square miles (342.9 km 2), of which 131.7 square miles (341.1 km 2) is land and 0.7 square miles (1.8 km 2) is water. The city is situated among the foothills of the Appalachian Mountains , and at 1,050 feet (320 m) above mean sea level, Atlanta has the highest elevation among major cities east of the ...
In August 2020, the U.S. Food and Drug Administration (FDA) became aware of nitrosamine impurities in certain samples of rifampin. [61] The FDA and manufacturers are investigating the origin of these impurities in rifampin, and the agency is developing testing methods for regulators and industry to detect the 1-methyl-4-nitrosopiperazine (MNP ...
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Atlanta (/ æ t ˈ l æ n t ə / ⓘ at-LAN-tə) [14] is the capital and most populous city in the U.S. state of Georgia.It is the seat of Fulton County, and a portion of the city extends into neighboring DeKalb County.
The rifamycin group includes the classic rifamycin drugs as well as the rifamycin derivatives rifampicin (or rifampin), rifabutin, rifapentine, rifalazil and rifaximin. Rifamycin, sold under the trade name Aemcolo, is approved in the United States for treatment of travelers' diarrhea in some circumstances. [1] [2] [3]
Rifapentine in pregnant women has not been studied, but animal reproduction studies have resulted in fetal harm and were teratogenic. If rifapentine or rifampin are used in late pregnancy, coagulation should be monitored due to a possible increased risk of maternal postpartum hemorrhage and infant bleeding. [2]
[1] [2] Based on projections, this region's urban areas will "expand 165%, from 17,800 km 2 in 2009 to 47,500 km 2 in 2060," [3] ultimately connecting the urban sprawl of Atlanta and Charlotte. [4] Researchers have expressed concern that this urban development will create a warmer climate along the corridor and increase flood risks in the region.
Scientists at the Italian drug company Achifar discovered rifabutin in 1975. (Eventually Archifar became part of Farmitalia Carlo Erba, a unit of the conglomerate Montedison which was subsequently bought by Pharmacia) This company's Adria Laboratories subsidiary filed for Food and Drug Administration (FDA) approval of rifabutin under the brand name Mycobutin in the early 1990s and the drug ...