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  2. Penicillin - Wikipedia

    en.wikipedia.org/wiki/Penicillin

    The Penicillium cells are grown using a technique called fed-batch culture, in which the cells are constantly subjected to stress, which is required for induction of penicillin production. While the usage of glucose as a carbon source represses penicillin biosynthesis enzymes, lactose does not exert any effect and alkaline pH levels override ...

  3. Production of antibiotics - Wikipedia

    en.wikipedia.org/wiki/Production_of_antibiotics

    Production of antibiotics is a naturally occurring event, that thanks to advances in science can now be replicated and improved upon in laboratory settings. Due to the discovery of penicillin by Alexander Fleming, and the efforts of Florey and Chain in 1938, large-scale, pharmaceutical production of antibiotics has been made possible.

  4. Penicillium - Wikipedia

    en.wikipedia.org/wiki/Penicillium

    Penicillium (/ ˌ p ɛ n ɪ ˈ s ɪ l i əm /) is a genus of ascomycetous fungi that is part of the mycobiome of many species and is of major importance in the natural environment, in food spoilage, and in food and drug production.

  5. Penicillin for Cats: Uses, Dosage, & Side Effects - AOL

    www.aol.com/lifestyle/penicillin-cats-uses...

    Penicillin for cats is an antibiotic medication derived from the Penicillium fungi. It falls under the beta-lactam class of antibiotics and is primarily used to treat bacterial infections.

  6. Penicillium rubens - Wikipedia

    en.wikipedia.org/wiki/Penicillium_rubens

    Penicillium rubens is a species of fungus in the genus Penicillium and was the first species known to produce the antibiotic penicillin. It was first described by Philibert Melchior Joseph Ehi Biourge in 1923. For the discovery of penicillin from this species Alexander Fleming shared the Nobel Prize in Physiology or Medicine in 1945. [1]

  7. β-Lactam antibiotic - Wikipedia

    en.wikipedia.org/wiki/Β-Lactam_antibiotic

    β-Lactam antibiotics are indicated for the prevention and treatment of bacterial infections caused by susceptible organisms. At first, β-lactam antibiotics were mainly active only against gram-positive bacteria, yet the recent development of broad-spectrum β-lactam antibiotics active against various gram-negative organisms has increased their usefulness.

  8. Penicillin-binding proteins - Wikipedia

    en.wikipedia.org/wiki/Penicillin-binding_proteins

    PBPs normally catalyze the cross-linking of the bacterial cell wall, but they can be permanently inhibited by penicillin and other β-lactam antibiotics. (NAM = N-acetylmuramic acid; NAG = N-acetylglucosamine) [2] Penicillin-binding proteins (PBPs) are a group of proteins that are characterized by their affinity for and binding of penicillin.

  9. Antibiotic - Wikipedia

    en.wikipedia.org/wiki/Antibiotic

    Some antibiotics may also damage the mitochondrion, a bacteria-derived organelle found in eukaryotic, including human, cells. [52] Mitochondrial damage cause oxidative stress in cells and has been suggested as a mechanism for side effects from fluoroquinolones. [53] They are also known to affect chloroplasts. [54]

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