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DMPX (3,7-dimethyl-1-propargylxanthine) is a caffeine analog which displays affinity to A 2 adenosine receptors, in contrast to the A 1 subtype receptors. [1] DMPX had 28× and 15× higher potency than caffeine in blocking peripheral and central NECA-responses. The locomotor stimulation caused by DMPX (ED 50 10 μmol/kg) was similarly higher ...
This resulted in the first drug analogue trial, where Scully claimed that he and his partners did nothing illegal, because they were producing ALD-52, which was not an illicit drug. However, as the prosecution claimed, there were problems with such a rationale—ALD-52 was claimed to readily undergo hydrolysis to LSD, and secondly, the ...
Common changes in nucleotide analogues. Nucleic acid analogues are used in molecular biology for several purposes: Investigation of possible scenarios of the origin of life: By testing different analogs, researchers try to answer the question of whether life's use of DNA and RNA was selected over time due to its advantages, or if they were chosen by arbitrary chance; [3]
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Analog Devices' DOCSIS 3.0-Compliant RF D/A Converter Operates at One-Third the Power of Competing Devices and Reduces PCB Space by 25 Percent ADI's 14-bit AD9129 and 11-bit AD9119 D/A converters ...
Like ALD-52, 1P-LSD is believed to act as prodrug for LSD via hydrolysis of the propionyl group. When 1P-LSD is incubated in human serum, [10] administered intravenously to rats, [11] or administered either orally or intravenously to human subjects, [12] high levels of LSD and relatively low levels of 1P-LSD are quickly detected, demonstrating that 1P-LSD is rapidly hydrolyzed into LSD in vivo ...
Analog Devices Sustainability Report Available Online NORWOOD, Mass.--(BUSINESS WIRE)-- Analog Devices, Inc. (NASDAQ: ADI), a global leader in high-performance semiconductors for signal processing ...
Analogue electronics (American English: analog electronics) are electronic systems with a continuously variable signal, in contrast to digital electronics where signals usually take only two levels. The term analogue describes the proportional relationship between a signal and a voltage or current that represents the signal.